Registry to learn about individuals with sex chromosome variations
Generating Advancements Through Longitudinal Analysis in X and Y Variations
This study is gathering information from people with sex chromosome variations, like Klinefelter syndrome, to better understand their health and improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 0 Days to 100 Years |
| Sex | All |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Aurora, Colorado) |
| Trial ID | NCT06373861 on ClinicalTrials.gov |
What this trial studies
GALAXY is a registry that aims to gather extensive information on individuals with sex chromosome aneuploidies, such as Klinefelter syndrome and other X&Y variations. The study collects data from medical records, including genetic tests, imaging, and medications, from patients seen at various clinics across the United States. By compiling this information, the registry seeks to enhance understanding and improve health outcomes for those affected by these conditions.
Who should consider this trial
Good fit: Ideal candidates include individuals of any age and gender with a genetically-confirmed diagnosis of a sex chromosome aneuploidy.
Not a fit: Patients without documented genetic testing confirming their diagnosis of sex chromosome aneuploidy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better health management and treatment strategies for individuals with sex chromosome aneuploidies.
How similar studies have performed: While this approach is observational and registry-based, similar studies have shown promise in improving understanding and treatment of genetic conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Genetically-confirmed diagnosis of a sex chromosome aneuploidy condition 2. Any age 3. Any gender 4. Informed consent for individuals \>18 years of age, parent/guardian permission for individuals \<18 or proxy-consent from legally authorized representative if impaired decision making Exclusion Criteria: a. Lack of documentation of genetic testing confirming SCA diagnosis
Where this trial is running
Aurora, Colorado
- Children's Hospital Colorado — Aurora, Colorado, United States (Recruiting)
Study contacts
- Principal investigator: Shanlee M Davis, MD, PhD — Children's Hospital Colorado
- Study coordinator: Shanlee M Davis, MD, PhD
- Email: shanlee.davis@childrenscolorado.org
- Phone: 720-777-6073
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.