Registry to investigate platelet function and genetics in heart disease
Development of a Prospective Cardiovascular Patient Cohort and Biobank and Provision of Genomic Analyses With Focus on Platelet Function and Platelet Mediated Inflammatory Processes
This study is trying to understand how genetics and platelet function affect heart disease and treatment responses to help improve care for people with heart problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Tuebingen Academic / other |
| Locations | 1 site (Tübingen, Baden Wuerttemberg) |
| Trial ID | NCT01417884 on ClinicalTrials.gov |
What this trial studies
This observational registry focuses on understanding the role of platelet function, genetics, proteomics, and metabonomics in cardiovascular disease. It aims to analyze the impact of genetic and non-genetic factors on the efficacy of platelet inhibition therapies, particularly in patients with ischemic and non-ischemic heart disease. By creating a prospective cohort with detailed phenotypic characterization, the study seeks to identify new molecular targets and biomarkers that could improve treatment outcomes for heart disease. High-quality bio-material will be collected to facilitate systematic examinations of these potential biomarkers.
Who should consider this trial
Good fit: Ideal candidates include patients with ischemic and non-ischemic heart disease who can provide informed consent.
Not a fit: Patients under 18 years old or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved personalized treatment strategies for patients with cardiovascular disease.
How similar studies have performed: Other studies have shown success in identifying genetic and molecular factors in cardiovascular disease, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with ischemic and non-ischemic heart disease 2. informed consent by patients or relatives in case of missing capacity to consent due to health status Exclusion Criteria: 1. Patients \<18 years 2. missing informed consent
Where this trial is running
Tübingen, Baden Wuerttemberg
- Medizinische Klinik und Poliklinik Tübingen, Cardiology Department, University Hospital Tübingen — Tübingen, Baden Wuerttemberg, Germany (Recruiting)
Study contacts
- Principal investigator: Tobias Geisler, Prof. Dr. — Ukt
- Study coordinator: Tobias Geisler, Prof. Dr.
- Email: tobias.geisler@med.uni-tuebingen.de
- Phone: +49 7071 29 82712
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.