Registry on local treatment methods for Myxoid Liposarcoma
Official title: International Prospective Registry on Local Treatment Approaches in Myxoid Liposarcomas
Run by The Netherlands Cancer Institute · NCT04699292 · Data updated 2026-11-12
This study is testing different local treatment options for people with Myxoid Liposarcoma to see which methods work best.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | The Netherlands Cancer Institute Academic / other |
| Locations | 1 site (Amsterdam) |
| Status | Recruiting |
| Started | January 18, 2021 |
| Main results expected | January 2031 |
| Study ends | January 2031 |
| Registry record updated | August 30, 2022 |
| Trial ID | NCT04699292 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with biopsy-proven Myxoid Liposarcoma and an ECOG performance status of 0-2.
✕Probably not a fit
Patients who have received prior radiotherapy to the target area or are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to prospectively evaluate various local treatment approaches for patients with Myxoid Liposarcoma (MLS). It will compare outcomes from different treatment modalities, including surgery and various radiation therapy doses, to confirm previous findings from the DOREMY trial. The study will collect and analyze data from multiple institutions to enhance understanding of effective treatment strategies for MLS.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for patients with Myxoid Liposarcoma.
How similar studies have gone: Other studies have shown promising results with similar treatment approaches, indicating potential for success in this registry.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Biopsy proven MLS, including the reciprocal chromosomal translocation t(12;16)(q13;p11) * ECOG PS 0-2 * Written informed consent to share coded information in this international Registry Exclusion Criteria: * Prior radiotherapy to the target area * Pregnancy
Where it's running
-
The Netherlands Cancer Institute
Amsterdam, Netherlands Recruiting
Study contacts
- Principal investigator: Rick Haas, MD/PhD — The Netherlands Cancer Institute
- Study coordinator: Rick Haas, MD/PhD
- Email: r.haas@nki.nl
- Phone: +31 20 512 9111
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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N-803 for progressive synovial sarcoma and myxoid/round cell liposarcoma after TCR-T therapy
This trial tests whether N-803 can safely boost lingering TCR-T immune cells and help people whose synovial sarcoma or myxoid/round cell liposarcoma has progressed after prior TCR-T treatment.
-
Testing mirdametinib with palbociclib for treating liposarcoma
This study is testing a new combination of two medications, mirdametinib and palbociclib, to see if they can help people with advanced liposarcoma feel better and improve their treatment options.
-
Evaluating treatments for non-rhabdomyosarcoma soft tissue sarcoma in young patients
This study is testing a combination of chemotherapy and radiation to see if it helps young patients with non-rhabdomyosarcoma soft tissue sarcoma live longer without their cancer coming back.
-
Exploring a new cancer treatment using PeptiCRAd-1 and checkpoint inhibitors
This study is testing a new cancer treatment that combines a special virus with immune therapy to see if it can help people with advanced cancer who haven't responded to other treatments.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.