Registry of treatments for brain arteriovenous malformation in China
Official title: Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China
Run by Beijing Tiantan Hospital · NCT04572568 · Data updated 2026-11-12
This study is testing a new treatment plan for brain arteriovenous malformations to see how well it works compared to standard care in patients in China.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Year to 80 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Beijing Tiantan Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | August 1, 2011 |
| Main results expected | April 1, 2032 |
| Study ends | April 1, 2033 |
| Registry record updated | May 23, 2022 |
| Trial ID | NCT04572568 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients aged 1-80 years with a confirmed diagnosis of brain AVM who have complete clinical and imaging data.
✕Probably not a fit
Patients who have received prior treatment for AVM or have a life expectancy of less than 6 months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multi-center, prospective registry study aimed at evaluating the long-term outcomes of brain arteriovenous malformation (AVM) treatments in China. Patients are divided into an experimental group, which receives a standardized multi-disciplinary treatment plan, and a control group, which does not. The study collects comprehensive data on patient demographics, imaging results, and treatment outcomes over a 20-year period. The goal is to establish a standardized diagnosis and treatment process for AVMs based on real-world evidence.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols and better outcomes for patients with brain arteriovenous malformations.
How similar studies have gone: Other studies have shown success with multi-disciplinary approaches in treating complex conditions, suggesting potential for positive outcomes in this study as well.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The diagnosis of AVM was confirmed with digital subtraction angiography (DSA) and/or magnetic resonance imaging(MRI). 2. Patients with complete clinical and imaging data. 3. Patient or patient's legal representative agreed to collection of information for this study and signed informed consent. Exclusion Criteria: 1. Received other treatment (surgery, embolization or SRS)before inclusion; 2. Expected survival time is less than 6 months; 3. Spinal AVMs; 4. Patients missing critical baseline and imaging data.
Where it's running
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Capital medical university affiliated Beijing Tiantan hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Principal investigator: Li Youxiang, MD — Beijing Neurosurgical Institute
- Study coordinator: Chen Yu, MD
- Email: chenyu_tiantan@126.com
- Phone: +8618801239327
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Liquid embolic treatment for brain arteriovenous malformations
This study will test a new liquid embolic agent against the Onyx system in adults (18–80) with brain arteriovenous malformations to see if it is as safe and effective.
-
Exploratory look at brain blood flow and metabolism before and after removing unruptured AVMs
This study tests brain perfusion and metabolism with PET imaging and neuropsychological tests in adults before and six months after surgical treatment for unruptured brain AVMs.
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Treatment options for brain arteriovenous malformations
This study is testing different treatment options for people with brain arteriovenous malformations to see which ones work best in preventing serious problems like stroke or death over ten years.
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Pulmonary embolism with right-to-left heart or lung shunts
This project will see if people with an acute pulmonary embolism who also have a right-to-left shunt (like a PFO or ASD) are more likely to have a stroke than PE patients without a shunt.
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Non-invasive detection of right-to-left shunts with the SONAS headband
This will test whether the SONAS headband can find right-to-left shunts in adults with hereditary hemorrhagic telangiectasia (HHT) who are already having a bubble heart ultrasound (TTCE).
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.