Registry of respiratory monogenic diseases in Chinese children

Beijing Children's Hospital

Observational Beijing Children's Hospital · NCT03528525

This study is trying to gather information from children with rare lung diseases to help understand their symptoms and improve future treatments.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages1 Month to 18 Years
SexAll
SponsorBeijing Children's Hospital Academic / other
Locations1 site (Beijing, Beijing Municipality)
Trial IDNCT03528525 on ClinicalTrials.gov

What this trial studies

This multicenter, prospective cohort study focuses on children diagnosed with respiratory monogenic diseases. It aims to collect and follow clinical information, including symptoms, lung function, chest imaging, and quality of life indicators over a period of five years. Patients will undergo standard diagnostic processes and their clinical data will be monitored to better understand these diseases. The study seeks to establish a comprehensive registry that can aid in future research and treatment approaches.

Who should consider this trial

Good fit: Ideal candidates are children aged 0-18 years with symptoms consistent with respiratory monogenic diseases.

Not a fit: Patients who cannot provide complete medical records or are unwilling to participate in the study will not benefit.

Why it matters

Potential benefit: If successful, this study could enhance understanding and management of respiratory monogenic diseases in children, leading to improved patient outcomes.

How similar studies have performed: While similar observational studies have been conducted, this specific focus on respiratory monogenic diseases in children is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age: 0-18 years, male and female.
2. Any organ system symptoms consistent with the diagnostic points of respiratory monogenic diseases.
3. Agree to retain specimens related to disease research and agree to store the specimens in the sample bank.
4. willing and able to cooperate with long-term follow-up.
5. The guardian of the child has a full understanding of the purpose of the study, a basic understanding of the clinical research program, and voluntarily allows the child to participate in the study and sign an informed consent form.

Exclusion Criteria:

1. It is unable to provide complete medical records or the current condition can not accept the diagnosis process
2. She or he cannot agree to participate in the study.

Where this trial is running

Beijing, Beijing Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Monogenic DiseasesDiseasesChildrenRespiratoryMonogenic diseasesChina
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.