Registry of patients with both cerebral and coronary atherosclerosis after acute ischemic stroke
Official title: Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
Run by Xuanwu Hospital, Beijing · NCT03788512 · Data updated 2026-11-12
This study is looking at patients who have both brain and heart artery problems after a stroke to see what factors affect their health and how to improve their care over the next five years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, BJ) |
| Status | Recruiting |
| Started | January 12, 2019 |
| Main results expected | December 2023 |
| Study ends | December 2027 |
| Registry record updated | January 11, 2022 |
| Trial ID | NCT03788512 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with ischemic stroke or transient ischemic attack within 30 days of symptom onset, who also have confirmed atherosclerosis in both cerebral and coronary arteries.
✕Probably not a fit
Patients with malignant tumors, poor organ function, or hematologic diseases with a life expectancy of less than five years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is an observational registry focused on patients hospitalized for acute ischemic cerebrovascular disease (AICVD) who exhibit atherosclerotic changes in both cerebral and coronary arteries. This single-center study aims to identify risk factors and develop prognostic models to improve patient outcomes. Clinical, imaging, and laboratory data will be collected at baseline, with follow-up assessments conducted over five years through patient self-reports and investigator follow-ups. The goal is to enhance diagnostic and therapeutic strategies for this high-risk patient population.
Why it matters
Potential benefit: If successful, this registry could lead to improved risk stratification and treatment strategies for patients with both cerebral and coronary atherosclerosis.
How similar studies have gone: While there is limited evidence specifically addressing the coexistence of cerebral and coronary atherosclerosis, similar observational studies have shown promise in understanding and improving outcomes in patients with atherosclerotic diseases.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosed as ischemic stroke or transient ischemic attack (TIA). 2. Less than 30 days after onset of ischemic stroke or TIA symptoms. 3. Extracranial or intracranial cerebral atherosclerosis confirmed by vascular ultrasound or CT angiograpgy or MR angiograpgy or digital substraction angiography. 4. Coronary atherosclerosis confirmed by CT angiograpgy or MR angiograpgy or digital substraction angiography; or with myocardial ischemia symptoms confirmed using electrocardiogram or echocardiography or cardiac MR; or with a history of percutaneous coronary intervention or coronary artery bypass graft. Exclusion Criteria: 1. With malignant tumors or poor organ functions or hematologic diseases, whose estimated life expectancy is less than 5 years. 2. Patients refuse to participate in the research.
Where it's running
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Xuanwu Hospital, Capital Medical University
Beijing, Bj, China Recruiting
Study contacts
- Study coordinator: Xin Ma, MD, PhD
- Email: maxin118@hotmail.com
- Phone: 13501390691
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using artificial intelligence to predict ischemic cerebrovascular disease early
This study is testing whether a new artificial intelligence tool can help doctors find patients at risk of serious strokes by looking at their health data.
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This study will test whether specific blood, cerebrospinal fluid, urine, and stool biomarkers can help diagnose and predict outcomes for people with ischemic stroke and related cerebrovascular conditions.
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Evaluating the effects of Calculus Bovis Sativus for ischemic cerebrovascular diseases
This study is testing whether a traditional Chinese medicine called Calculus Bovis Sativus can help improve brain health and reduce inflammation in people with ischemic cerebrovascular diseases like stroke.
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Prognosis prediction for patients with cardiovascular and cerebrovascular diseases using multi-omics
This study is trying to find out how different biological factors affect people with heart and brain blood vessel diseases to help doctors predict outcomes and personalize treatments for them.
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Examining blood pressure variability in non-hypertensive patients with ischemic cerebrovascular disease
This study looks at how changes in blood pressure over time affect non-hypertensive patients with ischemic cerebrovascular disease to see if it can help predict their risk of future health problems.
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Inhaled nitric oxide during mechanical clot removal for acute ischemic stroke
This test gives inhaled nitric oxide during mechanical clot removal to adults with acute ischemic stroke to see if it is safe and can help protect vulnerable brain tissue.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.