Registry of patients with both cerebral and coronary atherosclerosis after acute ischemic stroke
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
This study is looking at patients who have both brain and heart artery problems after a stroke to see what factors affect their health and how to improve their care over the next five years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, BJ) |
| Trial ID | NCT03788512 on ClinicalTrials.gov |
What this trial studies
The Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is an observational registry focused on patients hospitalized for acute ischemic cerebrovascular disease (AICVD) who exhibit atherosclerotic changes in both cerebral and coronary arteries. This single-center study aims to identify risk factors and develop prognostic models to improve patient outcomes. Clinical, imaging, and laboratory data will be collected at baseline, with follow-up assessments conducted over five years through patient self-reports and investigator follow-ups. The goal is to enhance diagnostic and therapeutic strategies for this high-risk patient population.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with ischemic stroke or transient ischemic attack within 30 days of symptom onset, who also have confirmed atherosclerosis in both cerebral and coronary arteries.
Not a fit: Patients with malignant tumors, poor organ function, or hematologic diseases with a life expectancy of less than five years may not benefit from this study.
Why it matters
Potential benefit: If successful, this registry could lead to improved risk stratification and treatment strategies for patients with both cerebral and coronary atherosclerosis.
How similar studies have performed: While there is limited evidence specifically addressing the coexistence of cerebral and coronary atherosclerosis, similar observational studies have shown promise in understanding and improving outcomes in patients with atherosclerotic diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosed as ischemic stroke or transient ischemic attack (TIA). 2. Less than 30 days after onset of ischemic stroke or TIA symptoms. 3. Extracranial or intracranial cerebral atherosclerosis confirmed by vascular ultrasound or CT angiograpgy or MR angiograpgy or digital substraction angiography. 4. Coronary atherosclerosis confirmed by CT angiograpgy or MR angiograpgy or digital substraction angiography; or with myocardial ischemia symptoms confirmed using electrocardiogram or echocardiography or cardiac MR; or with a history of percutaneous coronary intervention or coronary artery bypass graft. Exclusion Criteria: 1. With malignant tumors or poor organ functions or hematologic diseases, whose estimated life expectancy is less than 5 years. 2. Patients refuse to participate in the research.
Where this trial is running
Beijing, BJ
- Xuanwu Hospital, Capital Medical University — Beijing, Bj, China (Recruiting)
Study contacts
- Study coordinator: Xin Ma, MD, PhD
- Email: maxin118@hotmail.com
- Phone: 13501390691
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.