Clinical trial Recruiting at 1 site Observational Ages 18 to 85

Registry of patients with both cerebral and coronary atherosclerosis after acute ischemic stroke

Official title: Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry

Run by Xuanwu Hospital, Beijing · NCT03788512 · Data updated 2026-11-12

This study is looking at patients who have both brain and heart artery problems after a stroke to see what factors affect their health and how to improve their care over the next five years.

More Ischemic Cerebrovascular Disease trials

Quick facts

Study typeObservational
Ages18 Years to 85 Years
SexAll
Enrollment500 (estimated)
SponsorXuanwu Hospital, Beijing
Academic / other
Locations1 site (Beijing, BJ)
StatusRecruiting
StartedJanuary 12, 2019
Main results expectedDecember 2023
Study endsDecember 2027
Registry record updatedJanuary 11, 2022
Trial IDNCT03788512 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with ischemic stroke or transient ischemic attack within 30 days of symptom onset, who also have confirmed atherosclerosis in both cerebral and coronary arteries.

Probably not a fit

Patients with malignant tumors, poor organ function, or hematologic diseases with a life expectancy of less than five years may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is an observational registry focused on patients hospitalized for acute ischemic cerebrovascular disease (AICVD) who exhibit atherosclerotic changes in both cerebral and coronary arteries. This single-center study aims to identify risk factors and develop prognostic models to improve patient outcomes. Clinical, imaging, and laboratory data will be collected at baseline, with follow-up assessments conducted over five years through patient self-reports and investigator follow-ups. The goal is to enhance diagnostic and therapeutic strategies for this high-risk patient population.

Why it matters

Potential benefit: If successful, this registry could lead to improved risk stratification and treatment strategies for patients with both cerebral and coronary atherosclerosis.

How similar studies have gone: While there is limited evidence specifically addressing the coexistence of cerebral and coronary atherosclerosis, similar observational studies have shown promise in understanding and improving outcomes in patients with atherosclerotic diseases.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Diagnosed as ischemic stroke or transient ischemic attack (TIA).
2. Less than 30 days after onset of ischemic stroke or TIA symptoms.
3. Extracranial or intracranial cerebral atherosclerosis confirmed by vascular ultrasound or CT angiograpgy or MR angiograpgy or digital substraction angiography.
4. Coronary atherosclerosis confirmed by CT angiograpgy or MR angiograpgy or digital substraction angiography; or with myocardial ischemia symptoms confirmed using electrocardiogram or echocardiography or cardiac MR; or with a history of percutaneous coronary intervention or coronary artery bypass graft.

Exclusion Criteria:

1. With malignant tumors or poor organ functions or hematologic diseases, whose estimated life expectancy is less than 5 years.
2. Patients refuse to participate in the research.

Where it's running

  • Xuanwu Hospital, Capital Medical University
    Beijing, Bj, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.