Registry of older patients with Atrial Fibrillation in Europe
Evaluating the Efficacy and Risks of Anticoagulant Treatments in Multimorbid Frail Older Subjects With Atrial Fibrillation. The European Registry of Older Subjects With Atrial Fibrillation (EUROSAF)
This study looks at how different blood-thinning treatments affect older patients with Atrial Fibrillation while considering their overall health to see what works best for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Ente Ospedaliero Ospedali Galliera Academic / other |
| Locations | 1 site (Genova) |
| Trial ID | NCT02973984 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the clinical benefit and risk of anticoagulant treatments in older hospitalized patients with Atrial Fibrillation (AF). It focuses on understanding how different prognostic profiles, assessed by the Multidimensional Prognostic Index (MPI), influence treatment decisions and outcomes such as mortality and thromboembolic events. The study will analyze real-world data to determine the effectiveness of various anticoagulant therapies and their associated risks, particularly in the elderly population. By including a comprehensive geriatric assessment, the study seeks to provide insights into the optimal management of AF in older adults.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 65 years and older who are hospitalized for acute or chronic diseases and have a documented diagnosis of non-valvular Atrial Fibrillation.
Not a fit: Patients younger than 65 years or those who cannot provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify which older patients with Atrial Fibrillation are most likely to benefit from anticoagulant treatment, potentially improving survival rates.
How similar studies have performed: Other studies have shown success in using multidimensional prognostic indices to guide treatment decisions in older populations, indicating that this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: This is an observational study in which all consecutive patients admitted to the Geriatrics Units involved in the project will be screened for inclusion. The inclusion criteria are: 1. patients of both genders, aged 65 years and older 2. admitted to hospital for acute diseases or a relapse of chronic diseases 3. with a documented diagnosis of non valvular AF 4. who are willing to participate in the survey and give their informed consent Exclusion Criteria: 1. age less than 65 years 2. patients who have not provided informed consent
Where this trial is running
Genova
- S.C. Geriatria — Genova, Italy (Recruiting)
Study contacts
- Principal investigator: Alberto Pilotto, MD — Dipartimento: area delle cure geriatriche, ortogeriatria e riabilitazione - E.O. Ospedali Galliera - Genova Italy
- Study coordinator: Alberto Pilotto, MD
- Email: alberto.pilotto@galliera.it
- Phone: 0039 010 563
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.