Registry of Neuroblastic Tumours with Spinal Canal Involvement
Official title: Prospective Study Registry of Peripheral Neuroblastic Tumours Presenting With Spinal Canal Involvement (SCI)
Run by Associazione Italiana Ematologia Oncologia Pediatrica · NCT02559804 · Data updated 2026-11-12
This study is collecting information on young patients with neuroblastic tumors that affect the spinal canal to see how different factors impact their health over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Associazione Italiana Ematologia Oncologia Pediatrica Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Genova) |
| Status | Recruiting |
| Started | May 2014 |
| Main results expected | May 2029 |
| Study ends | May 2029 |
| Registry record updated | April 15, 2024 |
| Trial ID | NCT02559804 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children under 18 years diagnosed with peripheral neuroblastic tumours presenting with spinal canal involvement, regardless of symptom status.
✕Probably not a fit
Patients with neuroblastic tumours that do not involve the spinal canal or those who have received chemotherapy in the last six months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational, multi-centre registry aims to document the natural history of peripheral neuroblastic tumours that present with spinal canal involvement (SCI). It will evaluate the impact of various risk factors on neurological and orthopedic outcomes in affected patients. The study focuses on patients under 18 years old, both symptomatic and asymptomatic, and will collect data over a minimum follow-up period of five years. The findings may help refine treatment guidelines and improve patient management strategies.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols and outcomes for children with neuroblastic tumours presenting with spinal canal involvement.
How similar studies have gone: While there are few publications on this topic, most are retrospective; thus, this prospective approach is novel and may provide valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of peripheral neuroblastic tumour - peripheral neuroblastic tumour (neuroblastoma, ganglioneuroblastoma, ganglioneuroma) presenting with SCI, symptomatic or asymptomatic, independent of disease extension (stage), and clinical course (first diagnosis or relapse/progression) * No previous chemotherapy, except steroids, in the last 6 months * Age \<18 years * Minimal planned follow-up of 5 years * Parent/patient written informed consent (Appendix 1(A,B,C)) Exclusion Criteria: * Invasion of intervertebral foramina only
Where it's running
-
Istituto Giannina Gaslini
Genova, Italy Recruiting
Study contacts
- Principal investigator: Riccardo Haupt, MD — Istituto Giannina Gaslini Genova
- Study coordinator: Riccardo Haupt, MD
- Email: riccardohaupt@ospedale-gaslini.ge.it
- Phone: 01056363462
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.