Registry of long-term antithrombotic therapy for atrial fibrillation

Registry Dedicated to Assess the Risk of Ischemic and Hemorrhagic Complications of Long-term Antithrombotic Therapy in Patients With Atrial Fibrillation

Observational National Medical Research Center for Cardiology, Ministry of Health of Russian Federation · NCT04347187

This study looks at how safe and effective long-term blood-thinning treatments are for people with atrial fibrillation by tracking any complications they might have.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
Ages18 Years and up
SexAll
SponsorNational Medical Research Center for Cardiology, Ministry of Health of Russian Federation Government
Locations1 site (Moscow)
Trial IDNCT04347187 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the rates of ischemic and hemorrhagic complications associated with long-term antithrombotic therapy in patients diagnosed with atrial fibrillation. Conducted at a single center in Russia, the study will involve patients who meet specific criteria for antithrombotic treatment. By documenting outcomes over time, the study seeks to provide insights into the safety and efficacy of anticoagulants in this patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with documented atrial fibrillation and a CHA2DS2VASC score greater than 1.

Not a fit: Patients who are unwilling or unable to provide informed consent or have severe comorbid conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the risks associated with long-term antithrombotic therapy, potentially leading to improved treatment strategies for patients with atrial fibrillation.

How similar studies have performed: Other studies have explored antithrombotic therapy in atrial fibrillation, indicating that this approach has been previously tested, though the specific focus on long-term outcomes in this registry may provide novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Documented atrial fibrillation with CHA2DS2VASC \> 1

Exclusion Criteria:

* Subjects who are unwilling or unable to provide informed consent. ACS within 12 months before inclusion Severe CHF (NYHA IV) Stroke within 6 months before inclusion Severe liver or muscle disease Severe kidney disease / renal failure with creatinine \> 3 mg/dl Conceivable impossibility to come in touch with the patient or his family at 1-year after the intervention

Where this trial is running

Moscow

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial Fibrillationatrial fibrillation, coronary artery disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.