Registry of human skin and gut microbiomes
Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry
This study is trying to learn more about the different bacteria and fungi on the skin and in the gut of healthy people to see how things like age, diet, and medications affect them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospitals Cleveland Medical Center Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT05196061 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify and characterize the unique microbiome profiles of healthy volunteers across different body sites, including skin and gut. It will analyze how factors such as demographics, medical diagnoses, diet, and medications influence these microbiome profiles. The study will involve collecting data through questionnaires and biological samples, including stool, skin swabs, and oral rinses, to perform detailed correlation analyses of bacterial and fungal species. The goal is to understand the complex interactions within the microbiome and how they relate to individual characteristics.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy volunteers who can provide informed consent and complete all required procedures.
Not a fit: Patients who have used antibiotics or antifungals recently or are unable to complete the study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of the microbiome's role in health and disease, potentially leading to personalized medical approaches.
How similar studies have performed: While studies on microbiome profiling exist, this comprehensive registry approach focusing on both skin and gut microbiomes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Capable of giving informed consent. * Able and willing to complete all required specified study procedures Exclusion Criteria: * Antibiotic or antifungal use whether topical or systemic in the past 2 or 4 weeks, respectively. * Unable and/or unwilling to complete all required study procedures.
Where this trial is running
Cleveland, Ohio
- University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Mahmoud Ghannoum, PhD
- Email: mahmoud.ghannoum@uhhospitals.org
- Phone: 216-844-7834
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.