Clinical trial Recruiting at 1 site Observational Ages 18 and up

Registry of human skin and gut microbiomes

Official title: Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry

Run by University Hospitals Cleveland Medical Center · NCT05196061 · Data updated 2026-11-12

This study is trying to learn more about the different bacteria and fungi on the skin and in the gut of healthy people to see how things like age, diet, and medications affect them.

More Healthy Adult Male and Female Volunteers trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorUniversity Hospitals Cleveland Medical Center
Academic / other
Locations1 site (Cleveland, Ohio)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedDecember 31, 2030
Study endsDecember 31, 2030
Registry record updatedApril 13, 2026
Trial IDNCT05196061 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy volunteers who can provide informed consent and complete all required procedures.

Probably not a fit

Patients who have used antibiotics or antifungals recently or are unable to complete the study procedures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify and characterize the unique microbiome profiles of healthy volunteers across different body sites, including skin and gut. It will analyze how factors such as demographics, medical diagnoses, diet, and medications influence these microbiome profiles. The study will involve collecting data through questionnaires and biological samples, including stool, skin swabs, and oral rinses, to perform detailed correlation analyses of bacterial and fungal species. The goal is to understand the complex interactions within the microbiome and how they relate to individual characteristics.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of the microbiome's role in health and disease, potentially leading to personalized medical approaches.

How similar studies have gone: While studies on microbiome profiling exist, this comprehensive registry approach focusing on both skin and gut microbiomes is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Capable of giving informed consent.
* Able and willing to complete all required specified study procedures

Exclusion Criteria:

* Antibiotic or antifungal use whether topical or systemic in the past 2 or 4 weeks, respectively.
* Unable and/or unwilling to complete all required study procedures.

Where it's running

  • University Hospitals Cleveland Medical Center
    Cleveland, Ohio, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.