Registry of human skin and gut microbiomes
Official title: Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry
Run by University Hospitals Cleveland Medical Center · NCT05196061 · Data updated 2026-11-12
This study is trying to learn more about the different bacteria and fungi on the skin and in the gut of healthy people to see how things like age, diet, and medications affect them.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | University Hospitals Cleveland Medical Center Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | April 13, 2026 |
| Trial ID | NCT05196061 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy volunteers who can provide informed consent and complete all required procedures.
✕Probably not a fit
Patients who have used antibiotics or antifungals recently or are unable to complete the study procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify and characterize the unique microbiome profiles of healthy volunteers across different body sites, including skin and gut. It will analyze how factors such as demographics, medical diagnoses, diet, and medications influence these microbiome profiles. The study will involve collecting data through questionnaires and biological samples, including stool, skin swabs, and oral rinses, to perform detailed correlation analyses of bacterial and fungal species. The goal is to understand the complex interactions within the microbiome and how they relate to individual characteristics.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of the microbiome's role in health and disease, potentially leading to personalized medical approaches.
How similar studies have gone: While studies on microbiome profiling exist, this comprehensive registry approach focusing on both skin and gut microbiomes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Capable of giving informed consent. * Able and willing to complete all required specified study procedures Exclusion Criteria: * Antibiotic or antifungal use whether topical or systemic in the past 2 or 4 weeks, respectively. * Unable and/or unwilling to complete all required study procedures.
Where it's running
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States Recruiting
Study contacts
- Study coordinator: Mahmoud Ghannoum, PhD
- Email: mahmoud.ghannoum@uhhospitals.org
- Phone: 216-844-7834
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.