Registry of cell therapy for non-ischemic dilated cardiomyopathy
Official title: Registry of Cell Therapy in Non-Ischemic Dilated Cardiomyopathy
Run by University Medical Centre Ljubljana · NCT02445534 · Data updated 2026-11-12
This study collects information from patients with non-ischemic dilated cardiomyopathy who received their own cell therapy to see how well it works over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | University Medical Centre Ljubljana Academic / other |
| Locations | 1 site (Ljubljana) |
| Status | Recruiting |
| Started | January 2005 |
| Main results expected | January 2027 |
| Study ends | May 2027 |
| Registry record updated | July 3, 2024 |
| Trial ID | NCT02445534 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are adults aged 18-65 with a diagnosis of dilated cardiomyopathy and specific functional and clinical criteria.
✕Probably not a fit
Patients with acute multi-organ failure or a history of hematologic neoplasms will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry collects long-term clinical data from patients with non-ischemic dilated cardiomyopathy who have undergone autologous cell therapy. Patients treated at UMC Ljubljana between January 2005 and January 2018 will be followed up in a dedicated heart failure outpatient clinic. The aim is to analyze the data periodically to identify predictors of response to cell therapy, enhancing understanding of its long-term benefits.
Why it matters
Potential benefit: If successful, this registry could help identify which patients are most likely to benefit from cell therapy, potentially improving treatment outcomes.
How similar studies have gone: Previous studies have shown beneficial effects of stem cell therapy in similar patient populations, but this registry aims to provide more definitive long-term data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient inclusion criteria consisted of the following: age 18-65 years old, diagnosis of DCM according to the European Society of Cardiology position statement (9), optimal medical management for at least 6 months, left ventricular ejection fraction (LVEF) \<40%, and New York Heart Association functional Class III on stable medical therapy for at least 3 months before referral. Exclusion Criteria: * Patients with acute multi-organ failure or a history of hematologic neoplasms were not included.
Where it's running
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UMC Ljubljana
Ljubljana, Slovenia Recruiting
Study contacts
- Principal investigator: Bojan Vrtovec, MD, PhD — UMC Ljubljana
- Study coordinator: Bojan Vrtovec, MD, PhD
- Email: bojan.vrtovec@gmail.com
- Phone: +3861 522 1157
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.