Registry for understanding Parkinson's disease in China
Official title: The Chinese DENOVO Parkinson's Disease Registry
Run by Xiangya Hospital of Central South University · NCT05767151 · Data updated 2026-11-12
This study looks at how Parkinson's disease affects patients in China over time to see if certain signs can help predict how the disease will progress.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years to 75 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Status | Recruiting |
| Started | January 1, 2021 |
| Main results expected | January 1, 2031 |
| Study ends | January 1, 2031 |
| Registry record updated | March 14, 2023 |
| Trial ID | NCT05767151 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are newly diagnosed Parkinson's disease patients aged 30 to 75 with a disease duration of two years or less.
✕Probably not a fit
Patients with cognitive impairment or those already receiving antiparkinsonian therapy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the clinical characteristics and progression of Parkinson's disease (PD) in a longitudinal cohort of patients in China. It focuses on identifying biomarkers that can predict disease evolution and prognosis, addressing the heterogeneity of PD symptoms and progression rates. Data will be collected at baseline and during routine follow-up visits, including detailed patient histories and environmental factors. The study seeks to enhance understanding of PD's clinical features and potential genetic and environmental influences.
Why it matters
Potential benefit: If successful, this study could lead to better prediction of Parkinson's disease progression and more personalized treatment approaches for patients.
How similar studies have gone: Other studies have shown promise in identifying biomarkers for Parkinson's disease, but this specific approach focusing on a Chinese cohort is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Participants were diagnosed by MDS Clinical Diagnostic Criteria for PD 2. Disease duration ≤ 2 years at baseline 3. Hoehn-Yahr stage ≤2 at baseline 4. The age of PD patients ranges from 30 to 75 years old 5. Participants were naive to antiparkinsonian therapy 6. Able to Written informed consent Exclusion Criteria: 1. Participants were diagnosed with parkinsonism-syndrome 2. Participants were treated with antiparkinsonian drugs at baseline 3. Participants with cognitive impairment 4. Unable to Written informed consent
Where it's running
-
Xiangya Hospital of Central South University
Changsha, Hunan, China Recruiting
Study contacts
- Study coordinator: Jifeng Guo, Ph.D
- Email: guojifeng2003@163.com
- Phone: +8613974936815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.