Registry for trauma patients receiving massive blood transfusions
Massive Transfusion in Trauma Patient Registry
This study looks at trauma patients who receive a lot of blood transfusions to see how low calcium levels affect their blood's ability to clot and to help improve treatment practices.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Methodist Health System Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT06136715 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather data on trauma patients who undergo massive transfusion protocols (MTP) to better understand the incidence of hypocalcemia and its impact on coagulopathy during trauma resuscitation. It will analyze the relationship between the volume of blood products transfused and the resulting levels of hypocalcemia, with the goal of establishing standardized values that could inform clinical practices. The data collected will focus on best practices related to MTP, including component use, whole blood protocols, and electrolyte replacement strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are trauma patients aged 18 and older who are included in the Methodist Dallas Medical Center trauma registry and have received blood products as part of the MTP.
Not a fit: Patients under 18 years old will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could lead to improved management of trauma patients undergoing massive transfusions, potentially reducing mortality rates associated with hypocalcemia.
How similar studies have performed: While there is ongoing research into the effects of massive transfusion protocols, this specific approach to aggregating data on hypocalcemia in trauma patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • ≥18 years old * Included in the Methodist dallas medical center(MDMC) trauma registry * Flagged for MTP activation and/or \>1unit(U) blood product recorded in the first 24 hours Exclusion Criteria: * • \<18 years old
Where this trial is running
Dallas, Texas
- Methodist Dallas Medical Center — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Conner McDaniel, MD — Methodist Midlothian Medical Center
- Study coordinator: Bethany Brauer, MPH
- Email: MHSIRB@mhd.com
- Phone: 214-947-4681
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.