Registry for spontaneous intracranial hypotension and post-dural puncture headache

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry aims to collect structured information on the frequency, causes, symptoms, and diagnostic procedures related to spinal cerebrospinal fluid (CSF) leaks, which can lead to chronic headache syndromes and other serious health issues. It focuses on two main conditions: spontaneous intracranial hypotension (SIH) and post-dural puncture headache (PDPH), both of which are often misdiagnosed. By gathering data from patients with suspected spinal CSF leaks, the registry seeks to improve awareness and understanding of these conditions, ultimately aiding in timely diagnosis and treatment. The study is observational and does not involve specific interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with suspected spinal CSF leak based on one of the following

   * History of new orthostatic symptomes with or without prior spinal procedure
   * Imaging suggestive for spinal CSF leak
2. Informed consent

Exclusion Criteria:

a) Symptoms beeing conclusively explained by another known diagnosis

Where it's running

• Medical Center - University of Freiburg, Germany
  Freiburg im Breisgau, Germany Recruiting

Study contacts

• Study coordinator: Katharina Wolf, Dr. med.
• Email: katharina.wolf@uniklinik-freiburg.de
• Phone: +49 761 270-50010

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Cerebrospinal fluid leak after brain tumor surgery

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• Sealant versus no sealant to prevent CSF leaks after endoscopic endonasal skull base surgery

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• Dural Sealant Used After Neurosurgery to Help Ensure Watertight Closure

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  Recruiting Medprin Regenerative Medical Technologies Co., Ltd. · Riga · NCT07651826

• Comparing two dural sealants for preventing cerebrospinal fluid leaks after brain surgery

  This study is testing whether a new sealant called CraniSeal is as good as the existing DuraSeal at preventing leaks of spinal fluid after brain surgery.

  Recruiting at 7 sites Phase 4 Pramand LLC · Los Angeles, California and 7 other locations · NCT06406790

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.