Registry for rare ovarian and testicular stromal tumors
International Ovarian & Testicular Stromal Tumor Registry
This study is gathering information about rare ovarian and testicular stromal tumors to learn more about their causes and find better treatment options for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 0 Years to 100 Years |
| Sex | All |
| Sponsor | Children's Hospitals and Clinics of Minnesota Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT01970696 on ClinicalTrials.gov |
What this trial studies
This registry collects and analyzes clinical and biological data on ovarian and testicular stromal tumors to better understand their causes and treatment options. It gathers information through referrals from clinicians, families, and published case authors, focusing on factors such as clinical history, family history, imaging studies, and treatment outcomes. The registry also collects biological samples for genetic analysis, particularly looking at DICER1 mutations and miRNA expression, which may play a role in these tumors. The goal is to improve knowledge and treatment strategies for these rare cancers.
Who should consider this trial
Good fit: Ideal candidates include individuals with a current or previous diagnosis of ovarian or testicular stromal tumors.
Not a fit: Patients with adult granulosa cell tumors or those unable to provide informed consent may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could lead to improved understanding and treatment options for patients with rare ovarian and testicular stromal tumors.
How similar studies have performed: While this registry approach is novel for these specific tumors, similar registries have shown success in advancing understanding of rare cancers.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Previous or current diagnosis of an ovarian sex cord stromal including but not limited to: Sertoli-Leydig cell tumor, gynandroblastoma (now enrolling these patients on PPB/DICER1 Registry), juvenile granulosa cell tumor, Sertoli cell tumor, sex cord-stromal tumor with annular tubules or undifferentiated stromal tumor * Previous or current diagnosis of a testicular stromal tumor including but not limited to: juvenile granulosa cell tumor, Sertoli cell tumor, Leydig cell tumor or undifferentiated stromal tumor Exclusion Criteria: * Unable to provide informed consent/assent * Adult Granulosa cell tumor (unless otherwise specified by Medical Director)
Where this trial is running
Minneapolis, Minnesota
- Children's Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Kris Ann P Schultz, MD — Children's Minnesota
- Study coordinator: Anne Harris, MPH
- Email: anne.harris@childrensmn.org
- Phone: 612-813-5861
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.