Registry for Prosthodontic Rehabilitation in Cancer Patients Undergoing Jaw Reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to create a prospective database to collect patient demographics, surgical, dental, prosthetic, and quality of life (QOL) parameters for oncology patients undergoing jaw reconstruction. It focuses on patients with head and neck cancer, osteoradionecrosis, or medication-related osteonecrosis of the jaw who are eligible for fixed prosthodontic rehabilitation. The study will track these parameters during routine visits to better understand factors influencing the stability and success of prosthetic rehabilitation. The collaboration between oral and maxillofacial surgeons and prosthodontists aims to improve patient outcomes through a streamlined rehabilitation protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients of all ages
* Patients of all genders
* Patients with a histologically or clinically confirmed diagnosis of ORN, MRONJ, as classified by Ruggiero et al. (Ruggiero, et al., 2014) or carcinoma located in the oral cavity and jawbone, requiring segmental or total jaw resection
* Patients eligible for jaw and oral cavity reconstruction combined with immediate/delayed implant loading for fixed prosthetic rehabilitation
* Patients not eligible for conventional removable prosthetic rehabilitation

Exclusion Criteria:

* Patients with a clinically confirmed diagnosis of osteonecrosis not related to an oncological diagnosis or treatment
* Patients with medical contraindications for jaw reconstruction combined with immediate implant loading for fixed prosthetic rehabilitation
* Patients eligible for conventional removable prosthetic rehabilitation

Where it's running

• General Hospital Saint-John Bruges
  Bruges, Belgium Recruiting

Study contacts

• Principal investigator: Johan Abeloos, MD — Department of Oral and Maxillofacial Surgery, General Hospital Saint-John Bruges, Bruges, Belgium
• Study coordinator: Araceli Diez-Fraile, PhD
• Email: araceli.diez-fraile@azsintjan.be

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.