Registry for pregnancy outcomes after Exablate treatment for uterine fibroids

Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic Uterine Fibroids

Observational InSightec · NCT05386615

This study is looking to see how the Exablate treatment for uterine fibroids affects pregnancy outcomes in people who have had the procedure.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorInSightec Industry-sponsored
Locations6 sites (Los Angeles, California and 5 other locations)
Trial IDNCT05386615 on ClinicalTrials.gov

What this trial studies

This observational registry study aims to collect data on clinical pregnancy outcomes and treatment backgrounds for individuals who have undergone Exablate treatment for symptomatic uterine fibroids. Participants will be monitored for two years post-treatment to assess the impact of the Exablate procedure on pregnancy occurrences. The study is designed to gather safety data and inform potential updates to labeling regarding the treatment's effects on fertility.

Who should consider this trial

Good fit: Ideal candidates for this study are women who have been treated for symptomatic uterine fibroids using the Exablate system and have consented to participate in the registry.

Not a fit: Patients who have not undergone Exablate treatment or those with asymptomatic fibroids may not receive any benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the safety and efficacy of Exablate treatment regarding pregnancy outcomes for women with uterine fibroids.

How similar studies have performed: While this study is observational and focuses on pregnancy outcomes post-treatment, similar studies have shown promise in understanding the effects of fibroid treatments on fertility.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: - - Eligibility is as per the symptomatic fibroids device indication. - All registry-consented patients following the treatment of their fibroid(s) with the Exablate system. Exclusion Criteria: -

Where this trial is running

Los Angeles, California and 5 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Uterine FibroidUterine FibroidsExablate
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.