Registry for Polycystic Liver Disease in the UK

Polycystic Liver Disease Registry (UK)

Observational Portsmouth Hospitals NHS Trust · NCT04645251

This study is collecting information from people with polycystic liver disease in the UK to better understand how the condition affects them and what treatments might work best.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorPortsmouth Hospitals NHS Trust Government
Locations2 sites (Nijmegen and 1 other locations)
Trial IDNCT04645251 on ClinicalTrials.gov

What this trial studies

The Polycystic Liver Disease (PLD) registry in the UK is an observational study that aims to understand the natural progression of polycystic liver disease. It is part of a larger international registry led by Radboud University Medical Center in the Netherlands. The study collects both prospective and retrospective data, including responses from a validated questionnaire specific to PLD. This registry will help gather insights on patient characteristics, risk factors, symptoms, quality of life, and treatment strategies within the largest cohort of PLD patients to date.

Who should consider this trial

Good fit: Ideal candidates for this registry are patients with polycystic liver disease who have more than 10 liver cysts, including those with polycystic kidney disease.

Not a fit: Patients with fewer than 10 liver cysts will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of polycystic liver disease and improve patient management strategies.

How similar studies have performed: Other international registries have shown success in gathering valuable data on similar conditions, indicating that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with PLD with more than 10 liver cysts
* Patients with PKD and PLD with more than 10 liver cysts

Exclusion Criteria:

* Patients with PKD or PLD with less than 10 liver cysts

Where this trial is running

Nijmegen and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Polycystic Liver Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.