Registry for patients with undifferentiated connective tissue disease
Undifferentiated Connective Tissue Disease Registry
This study is collecting information from patients with undifferentiated connective tissue disease to better understand their condition and how it may develop into more specific diseases.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital for Special Surgery, New York Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT02234388 on ClinicalTrials.gov |
What this trial studies
This registry aims to collect and analyze clinical and emotional data from patients diagnosed with undifferentiated connective tissue disease (UCTD). By gathering information from medical records, clinical histories, and patient-reported symptoms, the registry seeks to enhance understanding of UCTD and its progression to more defined connective tissue diseases. The data collected will be stored for future research studies, which will be overseen by the Institutional Review Board at the Hospital for Special Surgery. Participation is open to patients receiving care at HSS for UCTD.
Who should consider this trial
Good fit: Ideal candidates include patients under the care of an HSS rheumatologist with specific autoantibody profiles and symptoms indicative of connective tissue disease.
Not a fit: Patients with well-defined connective tissue diseases or those under 18 years old may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could lead to improved prognostic predictions and better management strategies for patients with undifferentiated connective tissue disease.
How similar studies have performed: Other studies utilizing registries for autoimmune diseases have shown success in improving patient outcomes and understanding disease progression.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient under the care of an HSS rheumatologist * Positive ANA or a positive anti-ds DNA, anti-Ro/SS-A or other autoantibody on 2 or more occasions at least 12 weeks apart * One or more signs or symptoms of connective tissue disease, including but not limited to arthralgia, arthritis, myalgia, rash, sicca symptoms, pericarditis, pleuritis, pulmonary symptoms, peripheral neuropathy, photosensitivity, alopecia, oral or nasal ulcers, leucopenia, anemia, and abnormal nailfold capillaroscopy Exclusion Criteria: * Patients who meet criteria for well defined CTD including SLE, rheumatoid arthritis, polymyositis or dermatomyositis, systemic sclerosis, or antiphospholipid syndrome * Patients who are less than 18 * Those unable to give informed consent in English
Where this trial is running
New York, New York
- Hospital for Special Surgery — New York, New York, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.