Registry for patients with recurrent pregnancy loss
Official title: Prospective Recurrent Pregnancy Loss (ProRPL) Registry
Run by University of British Columbia · NCT05989178 · Data updated 2026-11-12
This study is collecting information from women who have had multiple pregnancy losses to see how different treatments and care options can help them over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years to 49 Years |
| Sex | Women only |
| Enrollment | 3000 (estimated) |
| Sponsor | University of British Columbia Academic / other |
| Locations | 1 site (Vancouver, British Columbia) |
| Status | Recruiting |
| Started | July 12, 2022 |
| Main results expected | December 31, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | December 13, 2024 |
| Trial ID | NCT05989178 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women who have experienced two or more pregnancy losses before 20 weeks of gestation.
✕Probably not a fit
Patients seeking care for reasons other than recurrent pregnancy loss will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry aims to collect and analyze data from patients experiencing recurrent pregnancy loss at the BC Women's Hospital. It will evaluate investigation practices, treatment options, and outcomes over time through a comprehensive approach that includes patient questionnaires and medical records. The program has been providing specialized care for 15 years and utilizes a collaborative model to support patients with clinical management and education. Data will be gathered from initial visits and follow-up questionnaires for up to five years.
Why it matters
Potential benefit: If successful, this registry could improve understanding and management of recurrent pregnancy loss, leading to better outcomes for affected patients.
How similar studies have gone: Other studies focusing on recurrent pregnancy loss have shown promise in improving patient outcomes, indicating that this approach may also be beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • Patients seen at the BC Women's Recurrent Pregnancy Loss Clinic with recurrent pregnancy loss, defined as ≥2 pregnancy losses before 20 weeks of gestation. Exclusion Criteria: • Patients at BC Women's Recurrent Pregnancy Loss Clinic seen for reasons other than recurrent pregnancy loss.
Where it's running
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BC Women's Hospital & Health Centre
Vancouver, British Columbia, Canada Recruiting
Study contacts
- Principal investigator: Mohamed A. Bedaiwy, MD, PhD — BC Women's Hospital & Health Centre
- Study coordinator: Mohamed A. Bedaiwy, MD, PhD
- Email: mohamed.bedaiwy@cw.bc.ca
- Phone: 604-875-2000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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G-CSF to help women with unexplained recurrent miscarriages
This study tests whether recombinant G-CSF can help women with two or more unexplained miscarriages who are undergoing IVF with tested embryos.
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Right DLPFC fNIRS neurofeedback for anxiety in women with recurrent pregnancy loss
This trial will see if right dorsolateral prefrontal cortex-targeted fNIRS closed-loop neurofeedback with slow-wave sound cues can reduce anxiety and improve heart-rate regulation in women with recurrent pregnancy loss aged 18–45.
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Hydroxychloroquine plus levothyroxine for improving live birth in euthyroid women with recurrent pregnancy loss and TPO antibodies
This trial will test whether adding hydroxychloroquine to levothyroxine increases the chance of a live birth for euthyroid women who have thyroid peroxidase antibodies and a history of recurrent pregnancy loss.
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Interactive support messaging for women with recurrent pregnancy loss
This study tests if a weekly messaging program that offers support and advice can help women who have had multiple pregnancy losses have healthier pregnancies and feel better overall.
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Using prednisolone to help women with unexplained recurrent miscarriages
This study is testing if taking prednisolone can help women who have had multiple unexplained miscarriages have a successful pregnancy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.