Registry for patients with poor grade aneurysmal subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicentric registry aims to define outcomes, predictors, treatment effects, and modifiers in patients suffering from poor grade aneurysmal subarachnoid hemorrhage. The research focuses on three main areas: early brain injury predictors in the emergency department, delayed brain injury predictors in the neurocritical care unit, and treatment strategies. Additionally, it investigates the incidence and impact of delayed cerebral ischemia and the long-term follow-up of patients who may experience significant improvement after 6-12 months. Standard management will be provided according to established guidelines.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients admitted to the emergency department because of aneurysmal subarachnoid hemorrhage of poor grade (IV-V) according to the WFNS classification.

Exclusion Criteria:

* Patients younger than 18 years old.
* Pregnant or breast-feeding patients.
* Aneurysmal subarachnoid hemorrhage due to trauma or vascular malformations other than cerebral aneurysms.

Where it's running

• IRCCS Bellaria
  Bologna, Italy Recruiting
• Azienda Ospedaliera Spedali Civili
  Brescia, Italy Recruiting
• Ospedale Vito Fazzi
  Lecce, Italy Recruiting
• IRCCS San Raffaele
  Milan, Italy Recruiting
• Ospedale Maggiore della Città di Novara
  Novara, Italy Recruiting
• Azienda Ospedaliero-Universitaria di Parma
  Parma, Italy Recruiting

Study contacts

• Principal investigator: Pietro Panni, P.I., M.D. — Department of Neuroradiology, Department of Neurosurgery
• Study coordinator: Pietro Panni, P.I., M.D.
• Email: panni.pietro@hsr.it
• Phone: +393406311389

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Understanding hemorrhage subtypes in perimesencephalic SAH and basilar artery perforator aneurysms

  This study tests whether different bleeding patterns in pmSAH, including potential basilar artery perforator aneurysms, relate to patient outcomes using a patient-reported EQ-5D measure.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT07923084

• Augmented kidney clearance in neurocritical care

  This project will test whether adults in the neuro-ICU with severe brain injury, stroke, seizures, or brain infections have faster kidney clearance (ARC) that can lower antiseizure and antibiotic drug levels.

  Recruiting at 3 sites University of Alberta · Lexington, Kentucky and 2 other locations · NCT07410624

• Lidocaine with or without steroid infusion into the middle meningeal artery for headaches after aneurysmal subarachnoid hemorrhage

  This study will try an infusion of lidocaine, with or without a steroid, into the middle meningeal artery to see if it reduces severe headaches and opioid use in adults recovering from aneurysmal subarachnoid hemorrhage.

  Recruiting Phase 2 The University of Texas Medical Branch, Galveston · Galveston, Texas · NCT07294118

• Nimodipine blood levels and enantiomer differences in aneurysmal subarachnoid hemorrhage.

  This project will test whether different amounts and the two forms of nimodipine get into the blood of adults with aneurysmal subarachnoid hemorrhage and whether that relates to their recovery.

  Recruiting at 3 sites University of Alberta · Richmond, Virginia and 2 other locations · NCT07065903

• Understanding brain and heart injuries after bleeding in the brain

  This study looks at how bleeding in the brain affects both the brain and the heart in adults to better understand the connection between these injuries.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06906432

• Remote ischemic conditioning after aneurysm clipping for ruptured brain aneurysms

  This test tries brief cycles of limb cuff inflation (remote ischemic conditioning) to see if it is safe and helps recovery in adults after surgical clipping of a ruptured brain aneurysm (aneurysmal subarachnoid hemorrhage).

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06819657

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.