Registry for patients with out-of-hospital cardiac arrest in Wroclaw
Wroclaw Out-Of-Hospital Cardiac Arrest Registry
This study is testing a new care program using advanced techniques like ECMO and angiography to see if it can help people who have a cardiac arrest outside of the hospital survive better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Wroclaw Medical University Academic / other |
| Locations | 1 site (Wroclaw) |
| Trial ID | NCT05132387 on ClinicalTrials.gov |
What this trial studies
This study assesses the effectiveness of a specialized care program for patients who experience out-of-hospital cardiac arrest. Participants will receive extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation (CPR) along with invasive procedures such as coronary and pulmonary angiography. The program aims to improve survival rates, which are currently below 10% for this patient population in Wroclaw, Poland. By institutionalizing this approach, the study seeks to provide a structured and effective treatment pathway for these critical cases.
Who should consider this trial
Good fit: Ideal candidates are individuals under 60 years old who have experienced a witnessed cardiac arrest with immediate CPR and a cardiac cause.
Not a fit: Patients over 60 years old, those with non-shockable rhythms, or severe concomitant illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly increase survival rates for patients experiencing out-of-hospital cardiac arrest.
How similar studies have performed: While ECMO-assisted CPR is a promising approach, this specific institutionalized program is novel and has not been previously tested in Wroclaw.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \< 60 years * witnessed sudden cardiac arrest with immediate CPR * supposed cardiac cause of the event * ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) at first medical contact with 3 unsuccessful defibrillations (no ROSC) * CPR conducted with Lund University Cardiopulmonary Assist System (LUCAS™) * Estimated transfer time from the scene to the Emergency Department \< 30 minutes. * End tidal carbon dioxide (ETCO2) \> 10 mmHg Exclusion Criteria: * Total presumed time from 112 call to ECMO implantation longer than 60 minutes * Age \< 18 years old or \> 60 years old; * Non-shockable initial rhythm * Unavailability of the automated CPR device * Unavailability of the catheterisation laboratory * Severe concomitant illness with decreased life expectancy * Severe body injury * Severe active bleeding * Drowning * Terminal cancer
Where this trial is running
Wroclaw
- Wroclaw University Hostpital — Wroclaw, Poland (Recruiting)
Study contacts
- Principal investigator: Wiktor Kuliczkowski, MD — Wroclaw Medical University
- Study coordinator: Wiktor Kuliczkowski, MD
- Email: wiktor.kuliczkowski@umw.edu.pl
- Phone: + 48 603 707 093
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.