Registry for patients with inflammatory breast cancer and MRD testing

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect data from participants diagnosed with inflammatory breast cancer (IBC) who may have undergone minimal residual disease (MRD) testing and are planning for surgery. The primary objective is to determine the incidence of MRD positivity before surgery, while secondary objectives include evaluating the feasibility of multi-institutional data collection, assessing the relationship between MRD and pathologic response, and understanding the impact of MRD results on patients' quality of life. Participants will also provide longitudinal MRD data to track recurrence and the effects of adjuvant therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female or males ≥18 years of age with the ability to understand and sign a written
* Participants who have a clinical diagnosis of stage III or IV inflammatory breast cancer (IBC).
* Participants who are planning to have or already completed a minimum of one blood draw for Signatera testing, for which the result and clinical data can be deposited into the study database.
* Participants must be within eight months of diagnosis and have not undergone breast surgery for this diagnosis of breast cancer.
* Participants must be English-speaking.

Exclusion Criteria:

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Where it's running

• MD Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Sadia Saleem, MD — M.D. Anderson Cancer Center
• Study coordinator: Sadia Saleem, MD
• Email: ssaleem@mdanderson.org
• Phone: 281-566-1900

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.