Registry for patients with coronary artery disease undergoing imaging
Multifactorial Analysis of Coronary Artery Plaques Using INtracoronary IMAGing for Exploration of Atherosclerotic Determinants and Progression - the MAIN-IMAGE Registry
This study collects information from patients with coronary artery disease who have had heart imaging to see how the details of their plaque might relate to heart problems in the future.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Goethe University Academic / other |
| Locations | 2 sites (Frankfurt am Main, Hesse and 1 other locations) |
| Trial ID | NCT06302777 on ClinicalTrials.gov |
What this trial studies
This observational registry collects data from patients with chronic or acute coronary syndrome who have undergone intracoronary imaging during cardiac catheterization. The study aims to analyze plaque characteristics identified through optical coherence tomography (OCT) or intravascular ultrasound (IVUS) to determine their association with adverse cardiac events, such as myocardial infarction and the progression of atherosclerosis. By gathering this information, the registry seeks to enhance understanding of coronary artery disease and improve patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this registry are patients with chronic or acute coronary syndrome who are scheduled for pre-intervention optical coherence tomography imaging.
Not a fit: Patients who are not undergoing optical coherence tomography imaging or those with other unrelated cardiac conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better risk stratification and management strategies for patients with coronary artery disease.
How similar studies have performed: Other studies utilizing intracoronary imaging techniques have shown promise in identifying plaque characteristics linked to adverse cardiac events, suggesting that this approach is supported by prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: patients undergoing pre-intervention optical coherence tomography imaging Exclusion Criteria: \-
Where this trial is running
Frankfurt am Main, Hesse and 1 other locations
- Frankfurt University Hospital — Frankfurt am Main, Hesse, Germany (Recruiting)
- Frankfurt University Hospital — Frankfurt, Germany (Recruiting)
Study contacts
- Study coordinator: Lena Seegers, MD
- Email: lena.seegers@herz-frankfurt.de
- Phone: +4963016666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.