Registry for patients with coronary artery disease undergoing imaging
Official title: Multifactorial Analysis of Coronary Artery Plaques Using INtracoronary IMAGing for Exploration of Atherosclerotic Determinants and Progression - the MAIN-IMAGE Registry
Run by Goethe University · NCT06302777 · Data updated 2026-11-12
This study collects information from patients with coronary artery disease who have had heart imaging to see how the details of their plaque might relate to heart problems in the future.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Goethe University Academic / other |
| Locations | 2 sites (Frankfurt am Main, Hesse and 1 other locations) |
| Status | Recruiting |
| Started | September 26, 2023 |
| Main results expected | September 26, 2028 |
| Study ends | September 26, 2031 |
| Registry record updated | March 12, 2024 |
| Trial ID | NCT06302777 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are patients with chronic or acute coronary syndrome who are scheduled for pre-intervention optical coherence tomography imaging.
✕Probably not a fit
Patients who are not undergoing optical coherence tomography imaging or those with other unrelated cardiac conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry collects data from patients with chronic or acute coronary syndrome who have undergone intracoronary imaging during cardiac catheterization. The study aims to analyze plaque characteristics identified through optical coherence tomography (OCT) or intravascular ultrasound (IVUS) to determine their association with adverse cardiac events, such as myocardial infarction and the progression of atherosclerosis. By gathering this information, the registry seeks to enhance understanding of coronary artery disease and improve patient outcomes.
Why it matters
Potential benefit: If successful, this study could lead to better risk stratification and management strategies for patients with coronary artery disease.
How similar studies have gone: Other studies utilizing intracoronary imaging techniques have shown promise in identifying plaque characteristics linked to adverse cardiac events, suggesting that this approach is supported by prior research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: patients undergoing pre-intervention optical coherence tomography imaging Exclusion Criteria: \-
Where it's running
-
Frankfurt University Hospital
Frankfurt am Main, Hesse, Germany Recruiting -
Frankfurt University Hospital
Frankfurt, Germany Recruiting
Study contacts
- Study coordinator: Lena Seegers, MD
- Email: lena.seegers@herz-frankfurt.de
- Phone: +4963016666
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.