Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Registry for patients with coronary artery disease undergoing imaging

Official title: Multifactorial Analysis of Coronary Artery Plaques Using INtracoronary IMAGing for Exploration of Atherosclerotic Determinants and Progression - the MAIN-IMAGE Registry

Run by Goethe University · NCT06302777 · Data updated 2026-11-12

This study collects information from patients with coronary artery disease who have had heart imaging to see how the details of their plaque might relate to heart problems in the future.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorGoethe University
Academic / other
Locations2 sites (Frankfurt am Main, Hesse and 1 other locations)
StatusRecruiting
StartedSeptember 26, 2023
Main results expectedSeptember 26, 2028
Study endsSeptember 26, 2031
Registry record updatedMarch 12, 2024
Trial IDNCT06302777 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are patients with chronic or acute coronary syndrome who are scheduled for pre-intervention optical coherence tomography imaging.

Probably not a fit

Patients who are not undergoing optical coherence tomography imaging or those with other unrelated cardiac conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry collects data from patients with chronic or acute coronary syndrome who have undergone intracoronary imaging during cardiac catheterization. The study aims to analyze plaque characteristics identified through optical coherence tomography (OCT) or intravascular ultrasound (IVUS) to determine their association with adverse cardiac events, such as myocardial infarction and the progression of atherosclerosis. By gathering this information, the registry seeks to enhance understanding of coronary artery disease and improve patient outcomes.

Why it matters

Potential benefit: If successful, this study could lead to better risk stratification and management strategies for patients with coronary artery disease.

How similar studies have gone: Other studies utilizing intracoronary imaging techniques have shown promise in identifying plaque characteristics linked to adverse cardiac events, suggesting that this approach is supported by prior research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

patients undergoing pre-intervention optical coherence tomography imaging

Exclusion Criteria:

\-

Where it's running

  • Frankfurt University Hospital
    Frankfurt am Main, Hesse, Germany
    Recruiting
  • Frankfurt University Hospital
    Frankfurt, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.