Registry for patients with coronary artery disease and atrial fibrillation
Official title: NEXUS Registry: An Outcomes Database Which Tracks Patient -Reported Outcomes After Percutaneous Coronary Intervention for Coronary Artery Disease Along With Surgical and Subcutaneous Ablation for the Management of Atrial Fibrillation.
Run by Cardiovascular Innovation and Research Institute · NCT03428048 · Data updated 2026-11-12
This study collects information from patients with coronary artery disease and atrial fibrillation to see how local care can improve their symptoms and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Cardiovascular Innovation and Research Institute Academic / other |
| Locations | 1 site (Glenwood Springs, Colorado) |
| Status | Recruiting |
| Started | March 2016 |
| Main results expected | March 2026 |
| Study ends | March 2030 |
| Registry record updated | June 1, 2020 |
| Trial ID | NCT03428048 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old diagnosed with coronary artery disease or atrial fibrillation who can provide informed consent.
✕Probably not a fit
Patients who are unable or unwilling to provide informed consent or have issues maintaining follow-up may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects data from patients with coronary artery disease and atrial fibrillation through disease-specific questionnaires, which are then combined with information from the National Cardiovascular Data Registry. The aim is to analyze this data continuously to improve the quality of care at a low-volume institution for procedures like percutaneous coronary intervention and endocardial ablation. By focusing on patient-reported outcomes and clinical effectiveness, the study seeks to demonstrate that quality care can be provided close to home, enhancing patient symptoms and overall quality of life.
Why it matters
Potential benefit: If successful, this study could lead to improved patient outcomes and access to quality cardiovascular care in low-volume centers.
How similar studies have gone: Other studies have shown success with similar registry approaches in improving quality of care and patient outcomes, indicating this method is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Candidates will be included in the study only if all the following conditions are met: 1. Age \>18 years 2. The subject has been informed of the nature of the study, agrees to its provisions, is able to comprehend, and has provided informed consent. 3. The subject is available for follow-up. 4. The subject has a diagnosis of coronary artery disease or Afib. Exclusion Criteria: Candidates will be excluded from the study if any of the following conditions are present: 1. Failure and / or inability and / or unwillingness to provide informed consent. 2. Likely problems, in the judgement of the investigators, with maintaining follow-up.
Where it's running
-
Valley View Hospital
Glenwood Springs, Colorado, United States Recruiting
Study contacts
- Principal investigator: Frank A Laws, MD — Valley View Hospital
- Study coordinator: Kim M Williams, MPH
- Email: kim.williams@vvh.org
- Phone: 970-384-7433
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
AI-powered ECG to help diagnose and predict outcomes in heart disease
Researchers test an AI-enhanced ECG to help diagnose and predict outcomes for people with cardiovascular diseases.
-
Flecainide safety in people with atrial fibrillation and stable coronary artery disease
This study tests whether flecainide is as safe as standard rhythm-control drugs for adults with atrial fibrillation and stable coronary artery disease.
-
μFR-guided Drug-Coated Balloon Angioplasty vs Angiography-guided Angioplasty in Coronary Artery Disease
This trial tests whether using computational μFR guidance during drug-coated balloon angioplasty is better than standard angiography guidance for people with de novo coronary artery lesions.
-
Pulsed Field vs Cryoballoon for Pulmonary Vein Isolation in Atrial Fibrillation
This trial tests whether pulsed field ablation can shorten the procedure for first-time PVI in AF patients compared with cryoballoon ablation, while keeping safety and effectiveness similar.
-
Pulsed Field Ablation vs Cryoablation for Atrial Fibrillation Under Deep Sedation
This trial tests whether pulsed field ablation (PFA) done under deep sedation works as well as cryoballoon ablation for treating atrial fibrillation, aiming to avoid general anesthesia.
-
Gastric Ultrasound Before CABG to See if Heart Function Changes Stomach Contents
This study checks whether people with weaker heart function before elective CABG have different stomach contents seen on ultrasound.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.