Registry for patients with bicuspid aortic valve disease

Bicuspid Aortic Valve and Ascending Aortic Aneurysm Registry

Observational University of Michigan · NCT01756222

This study is collecting information from people with bicuspid aortic valve disease to see how their condition changes over time and how different treatments work.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Michigan Academic / other
Locations1 site (Ann Arbor, Michigan)
Trial IDNCT01756222 on ClinicalTrials.gov

What this trial studies

This registry aims to collect comprehensive data on patients diagnosed with bicuspid aortic valve disease. It will assess patterns of aortic dilation and responses to medical therapy through serial imaging. Additionally, the registry will explore potential genetic markers associated with this condition, contributing to a better understanding of the disease's progression and treatment options.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 with a diagnosis of bicuspid aortic valve disease or a family history of the condition.

Not a fit: Patients who are unable or unwilling to provide informed consent will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could enhance the understanding of bicuspid aortic valve disease and improve patient management strategies.

How similar studies have performed: While this registry approach is common, the specific focus on bicuspid aortic valve disease may provide novel insights into this condition.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Any patient over the age of 18 who is able/willing to give informed consent with the diagnosis of bicuspid aortic valve disease, a family history of this disease or an ascending aortic aneurysm that is idiopathic can be included in the registry.

Exclusion Criteria:

* Patients unable or unwilling to give informed consent.

Where this trial is running

Ann Arbor, Michigan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bicuspid Aortic ValveBicuspid Aortic Valve DiseaseBAV
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.