Registry for patients undergoing cardiac surgery with Medtronic devices

SYMBIOSIS Post-Market Registry

Observational Medtronic Cardiac Surgery · NCT04241328

This study is collecting information from patients who have had heart surgery using Medtronic devices to see how safe and effective these products are in real-life situations.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
SexAll
SponsorMedtronic Cardiac Surgery Industry-sponsored
Locations14 sites (Vienna and 13 other locations)
Trial IDNCT04241328 on ClinicalTrials.gov

What this trial studies

This observational, multi-center registry aims to collect real-world data on the safety and performance of Medtronic cardiac surgery products. It focuses on identifying any new device-related complications and evaluating device success by monitoring adverse events and general performance. Patients enrolled in the registry will be followed according to routine care practices at their treating hospitals, ensuring comprehensive data collection on demographics and safety events.

Who should consider this trial

Good fit: Ideal candidates are patients undergoing procedures that utilize eligible Medtronic cardiac surgery products.

Not a fit: Patients currently participating in other interventional studies may not benefit from this registry due to potential confounding factors.

Why it matters

Potential benefit: If successful, this registry could enhance the safety and effectiveness of cardiac surgery devices, leading to improved patient outcomes.

How similar studies have performed: Other observational registries have successfully identified device-related complications and improved patient safety, indicating a positive precedent for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subject or legally authorized representative provides written data release and/or informed consent per institution and/or geographical requirements prior to discharge from participating registry hospital.
* Subject will undergo or underwent a procedure in which an eligible Medtronic CS product is/was used.

Exclusion Criteria:

* Currently participating in an interventional drug or device study which may induce confounding factor(s) to the results from this Registry

Where this trial is running

Vienna and 13 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.