Registry for patients treated with Transcatheter Aortic Valve Implantation in Switzerland

SwissTAVI Registry: Prospective, National, Multi-Center Registry of Patients Undergoing Transcatheter Aortic Valve Implantation

Observational Insel Gruppe AG, University Hospital Bern · NCT01368250

This study is collecting information from patients in Switzerland who have had a Transcatheter Aortic Valve Implantation to see how well the treatment works and how safe it is over time.

Quick facts

Study typeObservational
Enrollment20000 (estimated)
SexAll
SponsorInsel Gruppe AG, University Hospital Bern Academic / other
Locations2 sites (Bern and 1 other locations)
Trial IDNCT01368250 on ClinicalTrials.gov

What this trial studies

This observational registry collects clinical baseline, procedural, and follow-up data from patients treated with Transcatheter Aortic Valve Implantation (TAVI) across Switzerland. It aims to assess the safety and efficacy of CE approved TAVI devices by gathering data from multiple cardiovascular centers. The registry will track patient outcomes for up to 15 years, providing valuable insights into the long-term effectiveness of TAVI procedures. This initiative is designed to enhance the quality of care for high-risk patients with aortic valve disease.

Who should consider this trial

Good fit: Ideal candidates include patients with native aortic valve stenosis, native aortic valve regurgitation, or degenerated aortic bioprosthesis requiring treatment.

Not a fit: Patients who refuse informed consent or have contraindications for TAVI will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could improve treatment strategies and outcomes for patients with aortic valve disease.

How similar studies have performed: Other observational registries for TAVI have shown success in improving patient outcomes and treatment protocols.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Native aortic valve stenosis
* Native aortic valve regurgitation
* Degenerated aortic bioprosthesis requiring treatment

Exclusion Criteria

* Patients refuses informed consent to participate in the registry
* Contraindication for TAVI
* High probability of non-adherence to the follow up - requirements

Where this trial is running

Bern and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic Valve Disease MixedAortic valveHeart valveVARCTranscatheterMinimal-invasiveTAVITAVR
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.