Registry for patients receiving a cancer detection test

Falcon - The Exact Sciences Multicancer Early Detection (MCED) Real World Evidence (RWE) Registry

Observational Exact Sciences Corporation · NCT06589310

This study is creating a registry of patients who will take a new cancer detection test each year for three years to see how it helps with early cancer diagnosis and to compare their experiences with those who don’t take the test.

Quick facts

Study typeObservational
Enrollment25000 (estimated)
Ages50 Years to 80 Years
SexAll
SponsorExact Sciences Corporation Industry-sponsored
Drugs / interventionschemotherapy, immunotherapy, radiation
Locations2 sites (Evanston, Illinois and 1 other locations)
Trial IDNCT06589310 on ClinicalTrials.gov

What this trial studies

This observational study aims to create a multi-site registry of patients who will receive the Exact Sciences Multicancer Early Detection (MCED) test annually for three years. Participants will be monitored for cancer diagnoses, and data will be collected for five years following their initial test. The study will gather self-reported data on the testing experience and extract data from existing electronic health records for comparison with individuals who did not receive the MCED test.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 50 to 80 who are willing to undergo the MCED test and provide informed consent.

Not a fit: Patients with a history of invasive tumors or current cancer suspicion will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance early cancer detection and improve patient outcomes through better screening practices.

How similar studies have performed: Other studies utilizing similar early detection approaches have shown promise, indicating potential for success in this registry.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participant age at time of consent is between 50 and 80 years
* Agree to receive the Exact Sciences MCED test and follow-up imaging
* Willing and able to provide informed consent
* Access to a suitable technology and willing to complete surveys electronically

Exclusion Criteria:

* Any invasive tumor (excluding non-melanoma skin cancers) or hematological malignancy in the previous three years or current suspicion of cancer and/or in active treatment (e.g., chemotherapy, radiation therapy, immunotherapy, and/or surgery

Where this trial is running

Evanston, Illinois and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.