Registry for Parkinson's disease patients with GBA gene variants in China
Official title: The Chinese Parkinson's Disease With GBA Variants Registry
Run by Xiangya Hospital of Central South University · NCT03523065 · Data updated 2026-11-12
This study is creating a database to learn more about how GBA gene variants affect people with Parkinson's disease in China by looking at their symptoms and testing their blood for certain markers.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Status | Recruiting |
| Started | February 1, 2017 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | May 29, 2018 |
| Trial ID | NCT03523065 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are patients diagnosed with Parkinson's disease who have been identified as carrying GBA gene variants.
✕Probably not a fit
Patients without a diagnosis of Parkinson's disease or those who do not have GBA gene variants may not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Chinese Parkinson's disease with GBA variants Registry aims to create a comprehensive database of patients diagnosed with Parkinson's disease who carry GBA gene variants. This observational study will assess the clinical manifestations of these patients using various standardized scales and neurological tests. Additionally, blood samples will be analyzed for biomarkers associated with Parkinson's disease, such as uric acid and inflammatory markers. The goal is to better understand the impact of GBA variants on Parkinson's disease in the Chinese population.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of Parkinson's disease and lead to improved diagnosis and treatment strategies for patients with GBA gene variants.
How similar studies have gone: While the approach of creating a registry for specific genetic variants in Parkinson's disease is not novel, it has shown promise in other populations and could provide valuable insights in the Chinese context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with GBA gene variants. Exclusion Criteria: \-
Where it's running
-
Xiangya Hospital of Central South University
Changsha, Hunan, China Recruiting
Study contacts
- Study coordinator: Jifeng Guo, Ph.D.
- Email: guojifeng2003@163.com
- Phone: +8613974936815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.