Registry for Parkinson's disease patients with GBA gene variants in China
The Chinese Parkinson's Disease With GBA Variants Registry
Xiangya Hospital of Central South University · NCT03523065
This study is creating a database to learn more about how GBA gene variants affect people with Parkinson's disease in China by looking at their symptoms and testing their blood for certain markers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | Xiangya Hospital of Central South University (other) |
| Locations | 1 site (Changsha, Hunan) |
| Trial ID | NCT03523065 on ClinicalTrials.gov |
What this trial studies
The Chinese Parkinson's disease with GBA variants Registry aims to create a comprehensive database of patients diagnosed with Parkinson's disease who carry GBA gene variants. This observational study will assess the clinical manifestations of these patients using various standardized scales and neurological tests. Additionally, blood samples will be analyzed for biomarkers associated with Parkinson's disease, such as uric acid and inflammatory markers. The goal is to better understand the impact of GBA variants on Parkinson's disease in the Chinese population.
Who should consider this trial
Good fit: Ideal candidates for this registry are patients diagnosed with Parkinson's disease who have been identified as carrying GBA gene variants.
Not a fit: Patients without a diagnosis of Parkinson's disease or those who do not have GBA gene variants may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of Parkinson's disease and lead to improved diagnosis and treatment strategies for patients with GBA gene variants.
How similar studies have performed: While the approach of creating a registry for specific genetic variants in Parkinson's disease is not novel, it has shown promise in other populations and could provide valuable insights in the Chinese context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with GBA gene variants. Exclusion Criteria: \-
Where this trial is running
Changsha, Hunan
- Xiangya Hospital of Central South University — Changsha, Hunan, China (RECRUITING)
Study contacts
- Study coordinator: Jifeng Guo, Ph.D.
- Email: guojifeng2003@163.com
- Phone: +8613974936815
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parkinson Disease