Registry for managing and understanding outcomes of aortic arch repairs
CILCA Registry: Aortic Arch Variant With a Common Origin of the Innominate and Left Carotid Artery. Management and Outcomes of Open and Endovascular Repair.
This study is collecting information from about 500 patients with a specific type of aortic arch to see how different repair methods affect their recovery and health outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ospedale San Donato Academic / other |
| Locations | 1 site (San Donato Milanese, Milan) |
| Trial ID | NCT04995640 on ClinicalTrials.gov |
What this trial studies
This observational registry aims to gather clinical data and medical images from patients with a CILCA arch who are undergoing surgical or endovascular repair for aortic diseases. It focuses on understanding the unique anatomical features of the CILCA arch and their implications for postoperative complications. The study will enroll approximately 500 patients across multiple international centers, with follow-up assessments at 30 days, 12 months, and annually thereafter. The goal is to provide insights into the management strategies required for this specific anatomical variant.
Who should consider this trial
Good fit: Ideal candidates for this registry are adults aged 18 and older with a CILCA arch who are being treated for aortic diseases such as dissections or aneurysms.
Not a fit: Patients with contraindications to computed tomography or those who are pregnant may not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could improve surgical and endovascular treatment strategies for patients with CILCA arch, potentially reducing postoperative complications.
How similar studies have performed: While there is increasing literature on the CILCA arch, this registry represents a novel approach to systematically collect data on its management and outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years old * CILCA arch treated for an aortic disease (i.e. aortic dissection, aneurysm) Exclusion Criteria: * Contraindications to computed tomography (e.g. hypersensitivity to contrast media, renal failure); * Suspected or manifested pregnancy
Where this trial is running
San Donato Milanese, Milan
- IRCCS Policlinico San Donato — San Donato Milanese, Milan, Italy (Recruiting)
Study contacts
- Principal investigator: Massimiliano Maria Marrocco-Trischitta, MD, PhD — Ospedale San Donato , IRCCS
- Study coordinator: Massimiliano Maria Marrocco-Trischitta, MD, PhD
- Email: Massimiliano.MarroccoTrischitta@grupposandonato.it
- Phone: +390252774695
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.