Clinical trial Recruiting at 15 sites Observational

Registry for knee osteoarthritis pain management outcomes

Official title: Innovations in Genicular Outcomes Registry

Run by Pacira Pharmaceuticals, Inc · NCT05495334 · Data updated 2026-11-12

This study is trying to see how well different pain management treatments work for people with knee osteoarthritis and those who have had knee surgery.

More Knee Osteoarthritis trials

Quick facts

Study typeObservational
SexAll
Enrollment10000 (estimated)
SponsorPacira Pharmaceuticals, Inc
Industry-sponsored
Locations19 sites (Phoenix, Arizona and 18 other locations)
StatusRecruiting
StartedSeptember 23, 2021
Main results expectedJune 30, 2032
Study endsDecember 30, 2033
Registry record updatedJuly 23, 2026
Trial IDNCT05495334 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients planning to receive treatment for knee osteoarthritis pain within 60 days of screening.

Probably not a fit

Patients actively enrolled in other investigational trials or planning surgeries on knees other than the target knee may not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry captures prospective data on patients receiving various pain management therapies for chronic pain due to knee osteoarthritis or those undergoing knee arthroplasty. Treatments may include cryo nerve block, radiofrequency ablation, intra-articular corticosteroids, viscosupplementation, and opioids. The goal is to optimize pain management and assess outcomes related to these interventions. Patients will complete questionnaires via a registry application to provide valuable data on their experiences and treatment effectiveness.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of effective pain management strategies for knee osteoarthritis, leading to improved patient outcomes.

How similar studies have gone: Other studies have shown success in capturing patient outcomes through registries, indicating that this approach is promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Planned to receive treatment for knee OA pain including, but not limited to, knee injections, nerve blocking procedures, or knee arthroplasty within 60 days of screening
2. Able to understand the informed consent and assessment questionnaires and have the ability to complete them in the opinion of the investigator
3. Have access to a smartphone or internet access with a computer/tablet to complete the questionnaires using the registry application

Exclusion Criteria:

1. Actively enrolled in an investigational trial that would preclude patients from receiving the site's standard of care for knee OA pain or knee arthroplasty recovery protocol
2. Planning to have a surgery other than on the target knee

Where it's running

  • The MORE Foundation
    Phoenix, Arizona, United States
    Recruiting
  • Orthopedic Education and Research Institute of So Ca (Hoag)
    Irvine, California, United States
    Recruiting
  • Cedars-Sinai Medical Center
    Los Angeles, California, United States
    Recruiting
  • Florida Orthopaedic Associates
    DeLand, Florida, United States
    Recruiting
  • MidState Orthopedics and Sports Medicine
    Alexandria, Louisiana, United States
    Recruiting
  • Louisiana State University /Ochsner
    New Orleans, Louisiana, United States
    Recruiting
Show 13 more locations
  • Sinai Hospital of Baltimore
    Baltimore, Maryland, United States
    Recruiting
  • Orthopaedic Surgical Associates
    North Chelmsford, Massachusetts, United States
    Recruiting
  • OrthoNebraska Clinics
    Omaha, Nebraska, United States
    Recruiting
  • Northwell Health
    Garden City, New York, United States
    Recruiting
  • Oklahoma Surgical Hospital
    Tulsa, Oklahoma, United States
    Recruiting
  • Penn Highlands DuBois
    DuBois, Pennsylvania, United States
    Recruiting
  • University Orthopedics Center
    State College, Pennsylvania, United States
    Recruiting
  • Campbell Clinic
    Germantown, Tennessee, United States
    Recruiting
  • University of Utah
    Salt Lake City, Utah, United States
    Recruiting
  • Henry M Jackson Foundation for the Advancement of Military Medicine/Walter Reed National Military Medical Center
    Bethesda, Maryland, United States
    Terminated
  • Jersey City Medical Center
    Jersey City, New Jersey, United States
    Terminated
  • Genesee Orthopedics and Plastic Surgery (St. Elizabeth Med Center/ Apex Surgical Center)
    New Hartford, New York, United States
    Completed
  • Blue Nine Systems
    Asheville, North Carolina, United States
    Terminated

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.