Registry for infants with Retinopathy of Prematurity in Europe

European Disease Registry on Retinopathy of Prematurity (ROP)

Observational University Medicine Greifswald · NCT04939571

This study is collecting information about infants with Retinopathy of Prematurity across Europe to better understand how the condition varies and how it's treated.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
SexAll
SponsorUniversity Medicine Greifswald Academic / other
Locations59 sites (Salzburg and 58 other locations)
Trial IDNCT04939571 on ClinicalTrials.gov

What this trial studies

The EU-ROP registry is a multicenter observational study across Europe aimed at collecting clinical data on infants treated for Retinopathy of Prematurity (ROP). This registry will gather information on the clinical features, treatment patterns, and long-term outcomes of ROP in various European countries without any specific interventions. The study seeks to document the natural history of the disease and variations in its presentation among different populations. By compiling this data, the registry aims to enhance understanding and management of ROP.

Who should consider this trial

Good fit: Ideal candidates for this registry are infants diagnosed with ROP requiring treatment as per national guidelines.

Not a fit: Patients whose parents or legal guardians do not consent to the documentation and storage of personal data will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could improve the understanding of ROP and inform better treatment strategies for affected infants.

How similar studies have performed: Other observational registries have successfully contributed to the understanding of similar conditions, suggesting that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ROP requiring treatment according to the respective national ROP screening and treatment guidelines

Exclusion Criteria:

* Denial or absence of consent for documentation and electronic storage of personal data by parents or legal guardians

Where this trial is running

Salzburg and 58 other locations

+9 more sites — see ClinicalTrials.gov for the full list.

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Retinopathy of PrematurityROPanti-VEGFlaser coagulationepidemiologynon-interventional study
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.