Clinical trial Recruiting at 20 sites Observational Ages 18 and up

Registry for individuals diagnosed with lung cancer

Official title: Pulmonary Segmentectomy for Lung Cancer: A Real-World International Registry-TSOG 108

Run by Memorial Sloan Kettering Cancer Center · NCT06424327 · Data updated 2026-11-12

This study is collecting information from people with stage I lung cancer who are having surgery to see how they feel before and after the procedure to improve future treatments and care.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorMemorial Sloan Kettering Cancer Center
Academic / other
Drugs / interventionschemotherapy, radiation
Locations20 sites (Tucson, Arizona and 19 other locations)
StatusRecruiting
StartedMay 15, 2024
Main results expectedMay 15, 2029
Study endsMay 15, 2029
Registry record updatedSeptember 24, 2026
Trial IDNCT06424327 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a clinical stage I lung tumor suitable for segmentectomy.

Probably not a fit

Patients with lung cancer not suitable for segmentectomy or those with advanced stages of lung cancer may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect data from participants diagnosed with stage I lung cancer who are undergoing segmentectomy. Participants will complete questionnaires before surgery, and at two intervals post-surgery (2-4 weeks and 6 months). The study focuses on gathering patient-reported outcomes to better understand the experiences and recovery of lung cancer patients. The data collected will help inform future treatment approaches and patient care strategies.

Why it matters

Potential benefit: If successful, this study could enhance understanding of patient experiences and improve post-surgical care for lung cancer patients.

How similar studies have gone: While observational studies on lung cancer exist, this specific registry approach focusing on patient-reported outcomes is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years
* Patients suitable for segmentectomy, according to the treating surgeon
* Clinical Stage I with suspected NSCLC, classified preoperatively based on the AJCC TNM staging manual, 9th edition o Note: Tissue diagnosis of NSCLC is not required before enrollment. A pathologic diagnosis of NSCLC may be confirmed preoperatively with biopsy, intraoperatively with frozen section, or postoperatively on final pathology

Exclusion Criteria:

* Actively receiving lung cancer treatment or a history of lung cancer in the previous 5 years
* History of chemotherapy or radiation therapy for a previous lung cancer
* Synchronous secondary cancer in the lung or elsewhere in the body at the time of surgery
* Carcinoid tumors
* History of other malignancies within the past 3 years, with the exception of non-melanoma skin cancer, superficial bladder cancer, and carcinoma in situ of the cervix
* Actively receiving treatment for other malignancies
* Cases of lobectomy in conjunction with segmentectomy from another lobe and ≥2 segmentectomies from different lobes either en bloc or separate will be excluded from the primary analysis.

  * Multi-segmental resection from the same lobe is not a criterion for exclusion.

Where it's running

  • University of Arizona (Data Collection Only)
    Tucson, Arizona, United States
    Recruiting
  • University of California San Diego (Data collection)
    San Diego, California, United States
    Recruiting
  • Rush University Medical Center (Data collection only)
    Chicago, Illinois, United States
    Recruiting
  • Endeavor Health
    Evanston, Illinois, United States
    Recruiting
  • Massachusetts General Hospital Cancer Center (Data Collection Only)
    Boston, Massachusetts, United States
    Recruiting
  • Brigham and Women's Hospital (Data Collection Only)
    Boston, Massachusetts, United States
    Recruiting
Show 14 more locations
  • University of Michigan (Data Collection Only)
    Ann Arbor, Michigan, United States
    Recruiting
  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
    Basking Ridge, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
    Middletown, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)
    Montvale, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
    Commack, New York, United States
    Recruiting
  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)
    Harrison, New York, United States
    Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)
    New York, New York, United States
    Recruiting
  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)
    Uniondale, New York, United States
    Recruiting
  • Thomas Jefferson University Hospital (Data Collection Only)
    Philadelphia, Pennsylvania, United States
    Recruiting
  • ALLEGHENY HEALTH NETWORK (Data Collection Only)
    Pittsburgh, Pennsylvania, United States
    Recruiting
  • Baylor University Medical Center (Data Collection Only)
    Dallas, Texas, United States
    Recruiting
  • MD Anderson Cancer Center (Data Collection Only)
    Houston, Texas, United States
    Recruiting
  • University Health Network (Data Collection Only)
    Toronto, Ontario, Canada
    Recruiting
  • Centre Hospitalier de l'Université de Montreal (Data Collection Only)
    Montreal, Quebec, Canada
    Recruiting

Study contacts

  • Principal investigator: David Jones, MD — Memorial Sloan Kettering Cancer Center
  • Study coordinator: David Jones, MD
  • Email: jonesd2@mskcc.org
  • Phone: 212-639-6428

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.