Registry for Inappropriate Sinus Tachycardia and Postural Tachycardia Syndrome treatments

A Multicenter Patient Registry for Outcomes of Inappropriate Sinus Tachycardia and Postural Orthostatic Tachycardia Syndrome Treatment

Observational AtriCure, Inc. · NCT05107635

This study is collecting information on the safety and effectiveness of AtriCure devices used to treat people with Inappropriate Sinus Tachycardia or Postural Tachycardia Syndrome.

Quick facts

Study typeObservational
Enrollment500 (estimated)
SexAll
SponsorAtriCure, Inc. Industry-sponsored
Locations10 sites (Palo Alto, California and 9 other locations)
Trial IDNCT05107635 on ClinicalTrials.gov

What this trial studies

This registry aims to collect real-world safety and performance data on AtriCure devices used for ablating cardiac tissue in patients with Inappropriate Sinus Tachycardia (IST) or Postural Tachycardia Syndrome (POTS). It includes both retrospective and prospective data collection from multiple centers across the US and internationally. Patients who are scheduled for or have undergone treatment with AtriCure devices will be monitored to assess outcomes and safety profiles.

Who should consider this trial

Good fit: Ideal candidates for this registry are patients scheduled to undergo or who have already undergone a procedure for IST or POTS using AtriCure devices.

Not a fit: Patients currently enrolled in other studies that may affect the treatment outcomes for IST or POTS will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could provide valuable insights into the effectiveness and safety of AtriCure devices for treating IST and POTS, potentially improving patient care.

How similar studies have performed: Other studies involving similar observational approaches have shown success in capturing real-world data, making this registry a valuable addition to existing knowledge.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Subject is scheduled to undergo or has undergone a procedure to treat IST or POTS using one or more AtriCure devices.
2. Subject is willing to provide written informed consent (defined as legally effective, documented confirmation of a subject's voluntary agreement to participate in this Registry) or authorization per institution and geographical requirements

Exclusion Criteria:

1. Subject is enrolled in a concurrent study that may impact treatment outcome of IST or POTS.
2. Subject with exclusion criteria required by FDA or local governance

Where this trial is running

Palo Alto, California and 9 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Inappropriate Sinus TachycardiaPostural Tachycardia SyndromeSinus Node Sparing Hybrid Procedure
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.