Registry for Hantavirus Infections

Hantavirus Registry Gathers Knowledge on Epidemiology, Clinical Course, Prognostic Factors and Molecular Characteristics for Hantavirus Infections and Their Complications (HantaReg)

University of Cologne · NCT04323904

This study is collecting information from patients with hantavirus infections to see how the illness affects them and the costs of treatment, especially since these infections are becoming more common in Europe.

Quick facts

Study typeObservational
Enrollment200 (estimated)
SexAll
SponsorUniversity of Cologne (other)
Locations1 site (Cologne, North-Rhine Westfalia)
Trial IDNCT04323904 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect and analyze data on hantavirus infections, specifically focusing on hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). It will gather retrospective data from patients with confirmed hantavirus infections to better understand the clinical course, mortality rates, and associated healthcare costs. The study is motivated by the increasing incidence of hantavirus outbreaks in Europe and the need for more comprehensive data on these zoonotic infections.

Who should consider this trial

Good fit: Ideal candidates include individuals with confirmed hantavirus infections exhibiting clinical signs of nephropathia epidemica, HFRS, or HCPS.

Not a fit: Patients with serological or molecular evidence of hantavirus infection but without clinical symptoms of the specified syndromes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of hantavirus diseases and inform better management and treatment strategies for affected patients.

How similar studies have performed: While there is limited data on similar registries, the increasing incidence of hantavirus infections suggests a need for such observational studies, indicating potential for success in understanding these diseases.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Serological or molecular evidence of hantavirus infection and clinical evidence of nephropathia epidemica or hemorrhagic fever with renal syndrome (HFRS)
* Serological or molecular evidence of hantavirus infection and clinical evidence of hantavirus cardiopulmonary syndrome (HCPS)

Exclusion Criteria:

\- Serological or molecular evidence of hantavirus infection without clinical signs of nephropathia epidemica, HFRS or HCPS

Where this trial is running

Cologne, North-Rhine Westfalia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hantavirus Infections, Hemorrhagic Fever With Renal Syndrome, Nephropathia Epidemica, Hantavirus Cardiopulmonary Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.