Clinical trial Recruiting at 1 site Observational

Registry for Hantavirus Infections

Official title: Hantavirus Registry Gathers Knowledge on Epidemiology, Clinical Course, Prognostic Factors and Molecular Characteristics for Hantavirus Infections and Their Complications (HantaReg)

Run by University of Cologne · NCT04323904 · Data updated 2026-11-12

This study is collecting information from patients with hantavirus infections to see how the illness affects them and the costs of treatment, especially since these infections are becoming more common in Europe.

Quick facts

Study typeObservational
SexAll
Enrollment200 (estimated)
SponsorUniversity of Cologne
Academic / other
Locations1 site (Cologne, North-Rhine Westfalia)
StatusRecruiting
StartedMarch 4, 2020
Main results expectedMarch 2030
Study endsDecember 2030
Registry record updatedDecember 17, 2025
Trial IDNCT04323904 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with confirmed hantavirus infections exhibiting clinical signs of nephropathia epidemica, HFRS, or HCPS.

Probably not a fit

Patients with serological or molecular evidence of hantavirus infection but without clinical symptoms of the specified syndromes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect and analyze data on hantavirus infections, specifically focusing on hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). It will gather retrospective data from patients with confirmed hantavirus infections to better understand the clinical course, mortality rates, and associated healthcare costs. The study is motivated by the increasing incidence of hantavirus outbreaks in Europe and the need for more comprehensive data on these zoonotic infections.

Why it matters

Potential benefit: If successful, this study could enhance understanding of hantavirus diseases and inform better management and treatment strategies for affected patients.

How similar studies have gone: While there is limited data on similar registries, the increasing incidence of hantavirus infections suggests a need for such observational studies, indicating potential for success in understanding these diseases.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Serological or molecular evidence of hantavirus infection and clinical evidence of nephropathia epidemica or hemorrhagic fever with renal syndrome (HFRS)
* Serological or molecular evidence of hantavirus infection and clinical evidence of hantavirus cardiopulmonary syndrome (HCPS)

Exclusion Criteria:

\- Serological or molecular evidence of hantavirus infection without clinical signs of nephropathia epidemica, HFRS or HCPS

Where it's running

  • University Hospital of Cologne
    Cologne, North-Rhine Westfalia, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.