Registry for COVID-19 survivors to assess lung and heart health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the cardiopulmonary effects of COVID-19 by conducting a longitudinal assessment of patients who have recently tested positive for the virus. Participants will undergo various imaging techniques, including chest imaging, MRI, and echocardiograms, along with spirometry and blood tests to measure the severity of lung and heart injury. Additionally, the study will assess mental health indicators and quality of life outcomes in these patients. The goal is to better understand both the short- and long-term consequences of COVID-19 infection on respiratory and cardiovascular health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* have tested positive for SARS-CoV-2 and discharged from the ICU or,
* have tested positive for SARS-CoV-2 and have been discharged from hospital or,
* have tested positive for SARS-CoV-2 but was NOT hospitalized
* ages 18 and over, and
* competent and willing to sign informed consent and comply to all aspects of the protocol

CONTROL Inclusion Criteria

* No clinical history of COVID-19,
* No active clinical symptoms indicative of possible COVID-19,
* Ages 18 and over,
* competent and willing to sign informed consent and comply to all aspects of the protocol

Exclusion Criteria:

• Participants cannot sign consent

Any individual who meets any of the following criteria will be excluded from participation to the MRI or x-ray portion of the study:

* Participants who are pregnant or currently trying to get pregnant
* Participants unable to comply with any portion of the protocol (i.e. removing metals prior to entering the MRI scan room) or who have contraindications to MRI scanning (i.e., non-MRI-conditional pacemakers/defibrillators, pregnancy, ferromagnetic implants such as aneurysm clips, surgical clips, prostheses, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants)
* Persistent symptoms related to COVID-19 (in which case the patient may be re-screened later) As is done for all patients undergoing clinical MRI in our department, each patient will be screened for contraindications to MRI with a routine questionnaire prior to scanning.

CONTROL Exclusion Criteria

Patients with any of the following are excluded from as controls:

* Pace maker
* Poorly controlled diabetes
* Poorly controlled Restrictive lung disease
* Heart failure
* Parkinson's Disease
* Hypertension
* Any diagnosis or history of autonomic neuropathy

Where it's running

• NYU Langone Health
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Rany Condos, MD — NYU Langone Health
• Study coordinator: Ashley Witzl
• Email: PASCResearch@nyulangone.org
• Phone: 212-263-1208

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Collecting COVID-19 virus secretions and serum for developing treatments

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• Using donor-derived T cells to treat mild to moderate COVID-19

  This study is testing whether T cells from family members who have recovered from COVID-19 can help treat hospitalized patients with mild to moderate COVID-19.

  Recruiting Phase 1/2 New York Medical College · Valhalla, New York and 3 other locations · NCT04896606

• Observational study on the biology of COVID-19 in Saarland

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• Imaging immune activation in COVID-19 patients

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  Recruiting Phase 2 CellSight Technologies, Inc. · San Francisco, California · NCT04815096

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.