Registry for chronic rhinosinusitis outcomes
Official title: Real-Life Chronic Rhinosinusitis Outcome Registry
Run by Change Accelerator in Respiratory Care · NCT04670172 · Data updated 2026-11-12
This study is collecting information from people with chronic rhinosinusitis to see how the condition affects their lives and to learn more about the best treatments available.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 4550 (estimated) |
| Sponsor | Change Accelerator in Respiratory Care Industry-sponsored |
| Locations | 13 sites (Graz and 12 other locations) |
| Status | Recruiting |
| Started | January 1, 2021 |
| Main results expected | June 30, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | February 13, 2025 |
| Trial ID | NCT04670172 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients diagnosed with chronic rhinosinusitis who can use a mobile application.
✕Probably not a fit
Patients with malignancies of the sinonasal cavity, inverted papilloma, or unilateral disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry collects real-life data from patients with chronic rhinosinusitis attending specialist care centers across Europe. It aims to understand the burden of the disease, its impact on quality of life, and productivity loss, while also evaluating treatment effectiveness and identifying patients eligible for targeted biologic therapy. The data will be centralized in a pseudonymized database, utilizing a mobile application for patients and an online dashboard for physicians to facilitate ongoing research and insights. The study will also assess the societal costs associated with chronic rhinosinusitis and its treatment.
Why it matters
Potential benefit: If successful, this registry could lead to improved management and treatment options for patients with chronic rhinosinusitis.
How similar studies have gone: Other studies have successfully utilized outcome registries to improve understanding and treatment of chronic respiratory diseases, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Physician diagnosis of Chronic RhinoSinusitis * Capable of using a mobile application on a smartphone Exclusion Criteria: * Patients with malignancies of the sinonasal cavity * Patients with inverted papilloma * Patients with unilateral disease
Where it's running
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Graz University Hospital
Graz, Austria Recruiting -
University Hospital Vienna
Vienna, Austria Recruiting -
UCL Saint-Luc
Brussels, Belgium Recruiting -
UZ Ghent
Ghent, Belgium Recruiting -
UZ Leuven
Leuven, Belgium Recruiting -
Odense University Hospital
Odense, Denmark Recruiting
Show 7 more locations
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CHU Lille
Lille, France Recruiting -
Dusseldorf University Clinic
Düsseldorf, Germany Recruiting -
Policlinico Umberto I
Rome, Italy Recruiting -
UMC Amsterdam
Amsterdam, Netherlands Recruiting -
Hospital Clinic de Barcelona
Barcelona, Spain Recruiting -
Prof Claire Hopkins private practice
London, United Kingdom Recruiting -
Helsinki University Hospital
Helsinki, Finland Not yet recruiting
Study contacts
- Principal investigator: Claus Bachert, MD, PhD — UZ Ghent
- Study coordinator: Sven F Seys, PhD
- Email: sven.seys@galenus.health
- Phone: 0032 495 462585
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Applying Betamethasone Cream to Sinuses After Surgery for Chronic Rhinosinusitis
This study is testing if applying a special cream to the sinuses after surgery can help people with chronic sinus issues feel better when other treatments haven't worked.
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Using probiotics in nasal irrigation to treat chronic sinusitis
This study is testing if using a probiotic nasal rinse can help people with chronic sinusitis feel better after they've had sinus surgery, compared to using a regular saline rinse.
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Exploring the nasal microbiome's role in diseases like chronic rhinosinusitis and COVID-19
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.