Registry for chronic rhinosinusitis outcomes
Real-Life Chronic Rhinosinusitis Outcome Registry
This study is collecting information from people with chronic rhinosinusitis to see how the condition affects their lives and to learn more about the best treatments available.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4550 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Change Accelerator in Respiratory Care Industry-sponsored |
| Locations | 13 sites (Graz and 12 other locations) |
| Trial ID | NCT04670172 on ClinicalTrials.gov |
What this trial studies
This registry collects real-life data from patients with chronic rhinosinusitis attending specialist care centers across Europe. It aims to understand the burden of the disease, its impact on quality of life, and productivity loss, while also evaluating treatment effectiveness and identifying patients eligible for targeted biologic therapy. The data will be centralized in a pseudonymized database, utilizing a mobile application for patients and an online dashboard for physicians to facilitate ongoing research and insights. The study will also assess the societal costs associated with chronic rhinosinusitis and its treatment.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with chronic rhinosinusitis who can use a mobile application.
Not a fit: Patients with malignancies of the sinonasal cavity, inverted papilloma, or unilateral disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this registry could lead to improved management and treatment options for patients with chronic rhinosinusitis.
How similar studies have performed: Other studies have successfully utilized outcome registries to improve understanding and treatment of chronic respiratory diseases, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Physician diagnosis of Chronic RhinoSinusitis * Capable of using a mobile application on a smartphone Exclusion Criteria: * Patients with malignancies of the sinonasal cavity * Patients with inverted papilloma * Patients with unilateral disease
Where this trial is running
Graz and 12 other locations
- Graz University Hospital — Graz, Austria (Recruiting)
- University Hospital Vienna — Vienna, Austria (Recruiting)
- UCL Saint-Luc — Brussels, Belgium (Recruiting)
- UZ Ghent — Ghent, Belgium (Recruiting)
- UZ Leuven — Leuven, Belgium (Recruiting)
- Odense University Hospital — Odense, Denmark (Recruiting)
- Helsinki University Hospital — Helsinki, Finland (Not_yet_recruiting)
- CHU Lille — Lille, France (Recruiting)
- Dusseldorf University Clinic — Düsseldorf, Germany (Recruiting)
- Policlinico Umberto I — Rome, Italy (Recruiting)
- UMC Amsterdam — Amsterdam, Netherlands (Recruiting)
- Hospital Clinic de Barcelona — Barcelona, Spain (Recruiting)
- Prof Claire Hopkins private practice — London, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Claus Bachert, MD, PhD — UZ Ghent
- Study coordinator: Sven F Seys, PhD
- Email: sven.seys@galenus.health
- Phone: 0032 495 462585
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.