Registry collecting data on patients undergoing partial nephrectomy for kidney tumors

German National Registry for Nephron-Sparing Surgery

Association of Urologic Oncology (AUO) · NCT04681690

This study is collecting information from patients who are having surgery to remove part of their kidney due to tumors to see how different factors affect their care and recovery.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorAssociation of Urologic Oncology (AUO) (other)
Locations5 sites (Hof, Bavaria and 4 other locations)
Trial IDNCT04681690 on ClinicalTrials.gov

What this trial studies

The G-NeSS Registry is an observational study that collects prospective data on clinical and outcome variables from patients who are undergoing partial nephrectomy for localized renal masses. The study aims to analyze key factors that influence the quality of surgical care in this population, focusing on variables such as patient characteristics, tumor complexity, and surgical approach. Follow-up assessments are conducted at various intervals to gather long-term data on kidney function and patient outcomes. This comprehensive data collection will help refine surgical practices and improve patient care in the treatment of kidney neoplasms.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with localized renal masses suitable for nephron-sparing surgery.

Not a fit: Patients with urothelial cancer of the kidney or those who have previously undergone nephron-sparing surgery on the same kidney may not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could lead to improved surgical techniques and better patient outcomes for those undergoing nephron-sparing surgery.

How similar studies have performed: Other studies have shown success in utilizing registries to improve surgical outcomes, making this approach both relevant and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Written informed consent
* Localized renal parenchymal mass amenable to nephron-sparing surgery
* Adequate imaging of the abdomen (CT or MR with contrast)

Exclusion Criteria:

* Patient with (or suspected to have) urothelial cancer of the kidney
* Prior nephron-sparing surgery on ipsilateral kidney
* metastasized renal cell carcinoma

Where this trial is running

Hof, Bavaria and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Kidney Neoplasm

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.