Registry collecting data on microvascular dysfunction and coronary spasm
A Multicenter RegIstry on the Diagnosis of Patients with Chronic Angina and No Angiographic CoRonary Artery Stenosis (international Retrospective Collection of Anonymized Patient Data) - Searching a New Ach Spasm Definition
Johannes Gutenberg University Mainz · NCT06125392
This study is collecting information from patients with microvascular dysfunction and coronary spasm to better understand their experiences and improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Johannes Gutenberg University Mainz (other) |
| Locations | 1 site (Mainz, Rhineland-Palatinate) |
| Trial ID | NCT06125392 on ClinicalTrials.gov |
What this trial studies
The MICRO-SNAPE registry aims to gather data from patients being evaluated for microvascular dysfunction and coronary vasospasm across Europe and North America. This observational study focuses on better understanding the characteristics and phenotypes of patients suffering from these conditions, which significantly impact their quality of life and prognosis. Data will be collected retrospectively from clinical practices, ensuring anonymity while allowing for comprehensive analysis of the associations between various factors and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this registry are patients who have undergone coronary pressure and flow measurements in response to vasodilators.
Not a fit: Patients with hemodynamic instability or those under 18 years old may not benefit from participation in this registry.
Why it matters
Potential benefit: If successful, this registry could lead to improved diagnosis and management of coronary microvascular disease and vasospasm, enhancing patient care.
How similar studies have performed: While this registry approach is not novel, it builds on existing knowledge of microvascular dysfunction, and similar studies have shown the importance of detailed patient characterization in improving clinical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent combined measurements of coronary pressure and flow in at least 1 native coronary artery in response to endothelium dependent and independent vasodilators. Exclusion Criteria: * Hemodynamic instability * Age \<18 years
Where this trial is running
Mainz, Rhineland-Palatinate
- Center of Cardiology, Cardiology I, university hospital Mainz — Mainz, Rhineland-Palatinate, Germany (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Coronary Microvascular Disease, Coronary Vasospasm