Registry collecting data on microvascular dysfunction and coronary spasm
Official title: A Multicenter RegIstry on the Diagnosis of Patients with Chronic Angina and No Angiographic CoRonary Artery Stenosis (international Retrospective Collection of Anonymized Patient Data) - Searching a New Ach Spasm Definition
Run by Johannes Gutenberg University Mainz · NCT06125392 · Data updated 2026-11-12
This study is collecting information from patients with microvascular dysfunction and coronary spasm to better understand their experiences and improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Johannes Gutenberg University Mainz Academic / other |
| Locations | 1 site (Mainz, Rhineland-Palatinate) |
| Status | Recruiting |
| Started | September 30, 2023 |
| Main results expected | August 31, 2028 |
| Study ends | August 31, 2028 |
| Registry record updated | November 1, 2024 |
| Trial ID | NCT06125392 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are patients who have undergone coronary pressure and flow measurements in response to vasodilators.
✕Probably not a fit
Patients with hemodynamic instability or those under 18 years old may not benefit from participation in this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The MICRO-SNAPE registry aims to gather data from patients being evaluated for microvascular dysfunction and coronary vasospasm across Europe and North America. This observational study focuses on better understanding the characteristics and phenotypes of patients suffering from these conditions, which significantly impact their quality of life and prognosis. Data will be collected retrospectively from clinical practices, ensuring anonymity while allowing for comprehensive analysis of the associations between various factors and patient outcomes.
Why it matters
Potential benefit: If successful, this registry could lead to improved diagnosis and management of coronary microvascular disease and vasospasm, enhancing patient care.
How similar studies have gone: While this registry approach is not novel, it builds on existing knowledge of microvascular dysfunction, and similar studies have shown the importance of detailed patient characterization in improving clinical outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent combined measurements of coronary pressure and flow in at least 1 native coronary artery in response to endothelium dependent and independent vasodilators. Exclusion Criteria: * Hemodynamic instability * Age \<18 years
Where it's running
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Center of Cardiology, Cardiology I, university hospital Mainz
Mainz, Rhineland-Palatinate, Germany Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.