Registry assessing gender differences in hospitalized heart failure patients in Santiago

Gender Specific Registry in Subjects Hospitalized With Heart Failure in Santiago( GENESIS Registry): Pilot Heart Failure Registry Looking for Sex Analysis

Observational Fundacion de la Sociedad Chilena de Cardiologia y Cirugia Cardiovascular · NCT05960968

This study looks at how heart failure affects men and women differently in hospitalized patients in Santiago, Chile, to better understand their treatment and outcomes.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorFundacion de la Sociedad Chilena de Cardiologia y Cirugia Cardiovascular Academic / other
Locations1 site (Santiago, Santiago Metropolitan)
Trial IDNCT05960968 on ClinicalTrials.gov

What this trial studies

This observational registry aims to evaluate sex-related differences in the presentation, management, and prognosis of heart failure in patients admitted to hospitals in Santiago, Chile. The study will recruit approximately 500 patients over one year from two hospitals equipped with coronary units and cardiac imaging capabilities. Data will be collected through a descriptive cross-sectional survey, with informed consent obtained from all participants. The study will adhere to ethical guidelines and will be approved by the relevant ethics committees.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who are hospitalized with a diagnosis of acute or chronic heart failure requiring cardiovascular therapy.

Not a fit: Patients with acute Covid-19 infections or severe psychiatric disorders that impair assessment will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of gender-specific factors in heart failure, leading to improved treatment strategies for patients.

How similar studies have performed: While there have been studies on heart failure, this specific focus on gender differences in a Chilean population is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Patient with ≥ 18 years old
* Signed informed consent
* Admitted to the hospital with a :
* 1\) diagnosis of acute HF as the leading cause of admission, and in which a CV therapy is needed and prescribed (ie. diuretic, vasodilator, inotropic, device), or
* 2\) diagnosis of chronic HF is established during the patient hospitalization based on clinical, biochemical and/or imaging studies, and in which cardiovascular therapy is needed and prescribed (ie. diuretic, vasodilator, inotropic, device ) during the hospitalization.

Exclusion criteria:

* The patient presents a Covid 19 acute infection and/ or severe acute respiratory syndrome (SARS) -CoV 2 pneumonia is confirmed
* The patient presents a psychiatric decompensated disorder and/or a cognitive impairment which preclude assessment of this survey.

Where this trial is running

Santiago, Santiago Metropolitan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart FailureHeart Failure,GenderWomenEpidemiology
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.