Registry and initiative for Fibromuscular Dysplasia
Official title: The European/International FMD Registry and Initiative (FEIRI), a Prospective Study
Run by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT04804683 · Data updated 2026-11-12
This study is gathering information about Fibromuscular Dysplasia to better understand the condition and improve care for those affected.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | March 11, 2021 |
| Main results expected | December 31, 2022 |
| Study ends | March 10, 2031 |
| Registry record updated | May 5, 2022 |
| Trial ID | NCT04804683 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with established FMD, those with Spontaneous Coronary Artery Dissection (SCAD) showing FMD lesions, and individuals with atypical FMD presentations.
✕Probably not a fit
Patients whose diagnosis is based solely on ultrasound without confirmation from advanced imaging techniques will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This initiative aims to gather and analyze data on Fibromuscular Dysplasia (FMD) and related conditions globally. It will document demographic and arterial characteristics, evaluate the incidence of new FMD lesions, and investigate genetic and molecular mechanisms associated with the disease. Participants will provide clinical data retrospectively and prospectively, with an option to contribute to a biobank for further research. The study seeks to enhance understanding of FMD and its implications for patient care.
Why it matters
Potential benefit: If successful, this initiative could lead to improved diagnosis, treatment, and management of Fibromuscular Dysplasia.
How similar studies have gone: Other studies have shown promise in understanding FMD through genetic and clinical data collection, making this initiative a continuation of established research efforts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria:
(i) Patients with established FMD, i.e at least one string-of-beads (multifocal FMD) or focal stenosis (focal FMD).
(ii) Patients with Spontaneous Coronary Artery Dissection (SCAD) in whom at least one lesion of multifocal FMD (string-of beads) in extra-coronary arteries has been identified ("SCAD-FMD").
(iii) Patients with so-called "atypical FMD" or "FMD-like presentation", i.e. patients presenting with at least one dissection or 2 aneurysms \< 60-year-old, in the absence string-of-beads, focal stenosis or evidence of inherited arteriopathy.
Exclusion Criteria:
Diagnosis based only on ultrasound (need for computed tomographic angiography , magnetic resonance angiography or catheter-based angiography to confirm the diagnosis)
Where it's running
-
Cliniques Universitaires Saint-Luc
Brussels, Belgium Recruiting
Study contacts
- Principal investigator: Alexandre Persu, MD-PhD — Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Study coordinator: Alexandre Persu, MD-PhD
- Email: alexandre.persu@uclouvain.be
- Phone: 0032 2 764 63 06
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Observational study on spontaneous coronary artery dissection
This study is trying to learn more about spontaneous coronary artery dissection (SCAD) by following 3,000 patients over 10 years to better understand who it affects and how to treat it.
-
Understanding Fibromuscular Dysplasia and Related Arteriopathies
This study is trying to collect samples from people with Fibromuscular Dysplasia and related conditions to see what genes might be involved in these diseases.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.