Refitting Acuvue Oaysis Contact Lens Wearers into P7 Contact Lenses

How Does PRECISION7® for Astigmatism Perform in Current and Successful Acuvue® Oasys for Astigmatism Wearers?

This study is testing if people aged 18 to 40 who are happy with their Acuvue Oaysis contact lenses can comfortably switch to a new type of lens designed for astigmatism over a week.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 40 (estimated)
• Ages: 18 Years to 40 Years
• Sex: All
• Sponsor: Southern College of Optometry (other)
• Locations: 1 site (Memphis, Tennessee)
• Trial ID: NCT06955403 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the success of refitting satisfied wearers of Acuvue Oaysis contact lenses into Precision 7 contact lenses, which are designed for astigmatism and incorporate a unique moisturizing system. Participants will be adults aged 18 to 40 who have been wearing Acuvue Oaysis lenses for at least three months and have a specific range of astigmatism. The study will assess how well these individuals adapt to the new lenses over a one-week period, focusing on comfort and visual acuity. The findings will provide insights for practitioners on the feasibility of transitioning patients to this newer lens technology.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-40 who have been satisfied wearers of Acuvue Oaysis contact lenses and have astigmatism between 0.75 D and 2.50 D.

Not a fit: Patients with presbyopia or those who have previously worn Precision 7 contact lenses may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the comfort and vision quality for astigmatism patients by providing them with a more advanced contact lens option.

How similar studies have performed: While initial data on Precision 7 lenses are promising, this specific approach to refitting from Acuvue Oaysis has not been extensively tested in prior studies.

Eligibility criteria

• Inclusion Criteria: Adults, 18- to 40-year-old, AOA CL wearers with best-corrected 20/20 visual acuity or better.

* Participants will be required to have worn AOA CLs for at least 3 months in the past year and currently wearing these CLs.
* All participants will be required to have a CLDEQ-8 score \<12 while wearing their habitual CLs (AOA CLs) and to indicate that they are satisfied with AOA CLs (Yes/No).
* Participants will be required to be able to wear P7A CLs (astigmatism ≥0.75D OD/OS).
* Astigmatism ranging from 0.75 D to 2.50 D in each eye
* Participants will be required to wear the study CLs for ≥13 hours with no overnight wear
* Participants will be willing to wear the CL every day of the week, except during the washout period
* Participants will be required to provide a glasses prescription that is less than 3 years old
* \-
* Exclusion Criteria:
* \- Have presbyopia and/or need a reading add as determined during their initial manifest refraction
* Have worn P7A in the past
* Are past rigid CL wearers
* Have a history of being diagnosed with dry eye or ocular allergies
* Have known systemic health conditions that are thought to alter tear film physiology
* Have a history of viral eye disease
* Have a history of ocular surgery
* Have a history of severe ocular trauma
* Have a history of corneal dystrophies or degenerations
* Have active ocular infection or inflammation
* Are currently using isotretinoin-derivatives or ocular medications
* Are pregnant or breast feeding

Where this trial is running

Memphis, Tennessee

• The Southern College of Optometry — Memphis, Tennessee, United States (RECRUITING)

Study contacts

• Principal investigator: Chris Lievens — The Southern College of Optometry
• Study coordinator: Chris Lievens, OD

Conditions: Contact Lens Comfort