Reducing unnecessary medications in dementia patients with caregiver and provider prompts
Deprescribing in Patients Living with Dementia with Caregiver and Provider Nudges
NA · Brigham and Women's Hospital · NCT06347172
This study is testing whether reminders for doctors and caregivers can help reduce the use of risky medications in older patients with dementia.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 360 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Brigham and Women's Hospital (other) |
| Locations | 1 site (Boston, Massachusetts) |
| Trial ID | NCT06347172 on ClinicalTrials.gov |
What this trial studies
This study aims to implement a nudge intervention to help primary care providers and caregivers reduce the use of high-risk medications in patients living with dementia. The intervention includes electronic prompts for providers to discuss medication management with patients and their caregivers during visits. The study will assess the feasibility of this approach and evaluate its effectiveness in a larger clinical trial setting. It focuses on patients aged 65 and older who have been prescribed high-risk medications and have a diagnosis of dementia.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 65 and older with a diagnosis of dementia who have been prescribed high-risk medications.
Not a fit: Patients who are not currently prescribed high-risk medications or are younger than 65 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could lead to safer medication practices and improved health outcomes for patients living with dementia.
How similar studies have performed: Other studies have shown promise in using nudge interventions to improve medication management, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Primary care providers will be the primary unit of identification and randomization. Primary care providers inclusion criteria: * Providers within Brigham and Women's Hospital primary care practices * Having prescribed at least one of the high-risk medications of interest Eligible patients will be identified through this providers within the health care system. Patient inclusion criteria: * At least 65 years of age * Prescribed at least 90 pills of one of the high-risk medications of interest in the last 180 days in the EHR system, which most guidelines consider chronic use, and have a diagnosis of dementia in the EHR.
Where this trial is running
Boston, Massachusetts
- Mass General Brigham — Boston, Massachusetts, United States (RECRUITING)
Study contacts
- Principal investigator: Julie Lauffenburger, PharmD, PhD — Brigham and Women's Hospital
- Study coordinator: Julie Lauffenburger, PharmD, PhD
- Email: jlauffenburger@bwh.harvard.edu
- Phone: 617-525-8865
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia