Reducing stroke risk in African-American men

Not applicable Interventional Case Western Reserve University · NCT04402125

This study is testing a new support program for African American men who have had a stroke or TIA in the last five years to see if it can help reduce their risk of having another stroke.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment160 (estimated)
Ages18 Years to 90 Years
SexMale
SponsorCase Western Reserve University Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT04402125 on ClinicalTrials.gov

What this trial studies

This project is a 6-month prospective randomized controlled trial that evaluates the effects of a targeted management intervention (TEAM) compared to a wait-list control in African American men who have experienced a stroke or transient ischemic attack (TIA) within the past five years. The TEAM intervention is nurse-led and focuses on a holistic, person-centered approach that leverages the strengths of African American families and communities. It involves peer educator dyads who provide support and model healthy behaviors, encouraging participation from care partners. The intervention aims to be practical for implementation in various healthcare settings and seeks to address the high morbidity rates associated with stroke in this population.

Who should consider this trial

Good fit: Ideal candidates for this study are African American men aged 18 to 90 who have had a stroke or TIA in the past 10 years and are able to participate in group sessions.

Not a fit: Patients who do not identify as African American or who have not experienced a stroke or TIA within the specified timeframe may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce stroke risk and improve health outcomes for African American men.

How similar studies have performed: Other studies have shown success with similar community-based interventions aimed at reducing stroke risk, indicating that this approach has potential.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria for RCT participant:

1. Age range 18 to 90
2. Self-identified African American male
3. Have had a stroke or TIA in the past 10 years based on date of hospital discharge from an acute stroke program or Emergency Room/physician visit for TIA
4. Barthel Index (BI) score of \>= 40
5. Able to participate in group sessions

Inclusion Criteria for Care Partner

1. Age range from 18 to 90
2. Able to participate in group sessions

Inclusion criteria for peer educator:

1. Age range: from 18 to 90
2. Self-identified African American male
3. Have had a stroke or TIA
4. Able to participate in group sessions

Inclusion Criteria for Peer Educator Care Partner

1. Age range: from 18 to 90
2. Able to participate in group sessions
3. Is either a family member, friend or other individual who is important in an enrolled peer educator's stroke recovery OR the family member, friend or other individual of someone who has had a stroke or TIA and is/was important in their stroke recovery

Exclusion Criteria for RCT participant

1. Individuals who are unable or unwilling to provide written informed consent
2. Individuals who have had stroke due to sickle-cell disease

Exclusion Criteria for Care Partner participant 1. Individuals who are unable or unwilling to provide written informed consent

Exclusion Criteria for Peer Educator

1. Individuals who are unable or unwilling to provide written informed consent
2. Individuals who have had stroke due to sickle-cell disease

Exclusion Criteria for Peer Educator's Care Partner

1. Individuals who are unable or unwilling to provide written informed consent

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeTransient Ischemic Attack
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.