Reducing radiation exposure in the heart cath lab using RAMPART
The Radiation ProtEction for Dose RedUction in the Cardiac CathEter Lab Study: The REDUCE Trial
This study will test whether the RAMPART device reduces radiation exposure for doctors and nurses during coronary catheter procedures and allows them to wear lighter or no lead protection.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Liverpool Heart and Chest Hospital NHS Foundation Trust Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Liverpool) |
| Trial ID | NCT06875583 on ClinicalTrials.gov |
What this trial studies
Adult coronary intervention procedures performed with X-ray guidance will be randomized to either use the RAMPART radiation protection device or standard lead-based protection. Operators and cath lab team members will wear dosimeters to record per-procedure radiation dose, and doses will be compared between the two groups. The trial enrolls adults undergoing elective or urgent coronary intervention via right or left radial access and excludes femoral approaches, pregnancy, and those unable to consent. Secondary data will capture feasibility, operator comfort, and implications for use of lighter or no lead protection.
Who should consider this trial
Good fit: Ideal candidates are adult patients (18+) undergoing elective or urgent coronary intervention via the right or left radial artery who can provide informed consent.
Not a fit: Patients under 18, pregnant patients, those unable to consent, or procedures performed via femoral access are excluded and would not receive benefit from participation.
Why it matters
Potential benefit: If successful, RAMPART could significantly lower radiation doses to cath lab staff and allow them to use lighter or no lead aprons, improving long-term safety and comfort.
How similar studies have performed: Some prior small studies of supplemental shields have shown dose reductions, but randomized data specifically comparing RAMPART with standard protection are limited and this approach remains relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All procedures involving adult patients (\>18 year of age) * Male or female patients * Planned to undergo either an elective or urgent coronary intervention procedure involving ionising radiation in the cardiac catheter lab, via the right and or left radial arteries. Exclusion Criteria: * Procedures involving patients less than 18 years of age * Patients unable to give valid consent * Pregnancy * Femoral approach procedure
Where this trial is running
Liverpool
- Liverpool Heart & Chest Hospital — Liverpool, United Kingdom (Recruiting)
Study contacts
- Study coordinator: John D Hung, MBChB PhD MRCP(UK)
- Email: paula.walker@lhch.nhs.uk
- Phone: 0151 600 1657
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.