Reducing pain during vaccinations in infants using non-drug methods

The Effect of Breastfeeding and Maternal Holding on Reducing Pain During Vaccination in Infants

Not applicable Interventional University of Yalova · NCT06886412

This study tests if holding and breastfeeding can help reduce pain for healthy infants getting vaccinated.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment84 (estimated)
Ages1 Month to 6 Months
SexAll
SponsorUniversity of Yalova Academic / other
Locations1 site (Yalova)
Trial IDNCT06886412 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of non-pharmacological methods, specifically maternal holding and breastfeeding, in reducing pain experienced by infants during vaccinations. It aims to assess how these interventions can help infants cope with pain in a safe and cost-effective manner. The study involves healthy infants aged 4 weeks to 6 months who are scheduled for vaccination and have not received any analgesics prior to the procedure. By utilizing a randomized controlled design, the research seeks to provide evidence for best practices in infant pain management during vaccinations.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy infants aged between 4 weeks and 6 months who are scheduled for vaccination.

Not a fit: Patients who may not receive benefit from this study include those with chronic or mental illnesses, congenital anomalies, or those older than 6 months.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for infants during vaccinations, enhancing their overall vaccination experience.

How similar studies have performed: Other studies have shown success with similar non-pharmacological approaches to pain management in infants, indicating a promising avenue for further exploration.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being healthy,
* Aged between 4 weeks and 6 months,
* Parents have given verbal and written consent to participate in the study,
* Born at term (37 weeks of gestation or later),
* Scheduled for vaccination under the Ministry of Health's vaccination program,
* Not having taken analgesics/antipyretics in the last 4 hours before the procedure,
* Having a normal body temperature (between 36.5°C and 37.1°C).

Exclusion Criteria:

* Having a chronic or mental illness, or a congenital anomaly,
* Being older than 6 months,
* Having a body temperature above 37.1°C,
* Receiving analgesics, sedatives, or any other medication.

Where this trial is running

Yalova

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PainBreast FeedingMaternal BehaviorVaccinesNursingBreastfeedingMaternal holdingInfants
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.