Reducing oxygen levels during IVF to improve embryo development
Effect of Reducing the Oxygen Concentration From 5% to 2% on Intracytoplasmic Sperm Injection (ICSI) Outcome
NA · International Islamic Center for Population Studies and Research · NCT05924048
This study is testing if lowering oxygen levels during IVF can help embryos develop better and improve success rates for people trying to conceive.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 196 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | International Islamic Center for Population Studies and Research (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05924048 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of lowering the oxygen concentration from 5% to 2% during the process of Intracytoplasmic Sperm Injection (ICSI) on embryo development outcomes. It aims to understand how different oxygen levels affect the metabolic processes of embryos and their ability to reach the blastocyst stage. By creating a more controlled in vitro environment that mimics natural conditions, the study seeks to enhance embryo viability and improve success rates in IVF treatments. The research is based on previous findings that suggest lower oxygen levels may lead to better blastulation rates.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 20-35 with normal oocyte morphology undergoing IVF.
Not a fit: Patients with fewer than five embryos or those with male factor infertility may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the success rates of IVF treatments for patients.
How similar studies have performed: Previous studies have shown promising results with lower oxygen concentrations in embryo culture, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Female age 20-35 years. Oocytes with normal morphology. Exclusion Criteria: * Embryo number less than 5. Male factor.
Where this trial is running
Cairo
- International Islamic Center — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Ahmed El Sayed Sabry
- Email: ahmedsabry7787@gmail.com
- Phone: 01098609545
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: IVF