Reducing opioid use after neck surgery with a nerve block
The Opioid Sparing Effect of an Inter-semispinalis Plane Block on Postoperative Pain Control in Posterior Cervical Spine Surgery
This study is testing if a special nerve block can help people having neck surgery use less opioids for pain relief compared to standard pain management.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Stony Brook University Academic / other |
| Locations | 1 site (Stony Brook, New York) |
| Trial ID | NCT06570577 on ClinicalTrials.gov |
What this trial studies
This research evaluates the effectiveness of an Inter-semispinalis plane (ISP) nerve block in reducing the need for opioids in patients undergoing posterior cervical spine surgery. Participants will receive either the nerve block or standard pain management, allowing researchers to compare pain levels, opioid consumption, and hospital discharge times between the two groups. The ISP block is a minimally invasive procedure that targets specific nerves in the neck to provide pain relief, potentially leading to improved recovery outcomes and reduced opioid-related side effects.
Who should consider this trial
Good fit: Ideal candidates are individuals scheduled for posterior cervical spine surgery from C2 to C7.
Not a fit: Patients undergoing emergency procedures, those with certain medical conditions, or those requiring complex surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid consumption and improve recovery times for patients after neck surgery.
How similar studies have performed: While some studies have shown promise for nerve blocks in pain management, further data on the ISP block's safety and efficacy are still needed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Having Posterior Cervical Spine Surgery from C2 - C7, which may extend to the upper thoracic vertebrae, inclusive to T3. * Capacity to provide informed consent Exclusion Criteria: * Fusion and decompression due to trauma * Emergent procedures * Patient is on a medication-assisted treatment, e.g., buprenorphine, naltrexone or methadone. * There is an infection near or in the area of neck where the block will be placed. * The patient is having a complicated surgery or a revision surgery * Female patient with a positive pregnancy test on the day of surgery (hospital standard-of-care). * Patient has Diabetes * Patients who have had a prior adverse reaction to bupivacaine or dexamethasone * Patients with Glucose-6-phosphate dehydrogenase deficiency or congenital or idiopathic methemoglobinemia
Where this trial is running
Stony Brook, New York
- Stony Brook University Hospital — Stony Brook, New York, United States (Recruiting)
Study contacts
- Principal investigator: Eman Nada, MBBCH — Stony Brook University Hospital
- Study coordinator: Eman Nada, MBBCH
- Email: Eman.Nada@stonybrookmedicine.edu
- Phone: 516-287-9118
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.