Reducing opioid use after laparoscopic hiatal hernia surgery
Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia
This study is testing if using less opioids during anesthesia for hiatal hernia surgery can help patients recover better and use fewer pain medications after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Endeavor Health Academic / other |
| Locations | 1 site (Evanston, Illinois) |
| Trial ID | NCT05953428 on ClinicalTrials.gov |
What this trial studies
This clinical trial is a prospective randomized, double-blinded, controlled study enrolling 75 patients undergoing laparoscopic hiatal hernia repair. Participants will be randomly assigned to receive either an opioid sparing anesthesia protocol or an opioid-based anesthesia protocol. The study aims to determine if the opioid sparing approach can reduce opioid consumption at discharge and improve postoperative recovery outcomes, including pain scores, incidence of nausea and vomiting, and overall hospital costs. The trial will also assess the impact on rehospitalization and reoperation rates.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-90 undergoing elective laparoscopic hiatal hernia surgery.
Not a fit: Patients requiring urgent or emergent hiatal hernia surgery or those with adverse reactions to the study medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid consumption and improve recovery for patients undergoing laparoscopic hiatal hernia repair.
How similar studies have performed: Preliminary results from similar studies suggest that opioid sparing protocols can effectively reduce postoperative opioid use, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients from 18-90 years old who are undergoing laparoscopic hiatal hernia surgery * Elective Laparoscopic hiatal hernia repair Exclusion Criteria: * Patients receiving urgent or emergent hiatal hernia surgery * Patients receiving hiatal hernia surgery without laparoscopy * Patients with adverse reactions (e.g., anaphylaxis, rash) to any of the drugs in the OBA or OSA protocols.
Where this trial is running
Evanston, Illinois
- NorthShore University HealthSystem — Evanston, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Steven Greenberg, MD — Endeavor Health
- Study coordinator: Steven Greenberg, MD
- Email: sgreenberg@northshore.org
- Phone: 847-570-2760
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.